Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Methyl bromide optic atrophy.

C T Chavez, R S Hepler, B R Straatsma

    American Journal of Ophthalmology
    |June 15, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Methyl bromide poisoning caused systemic and neuro-ophthalmic issues in a fumigation assistant. Symptoms included vision loss and nerve damage, with no improvement after one year.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Density-profile imaging using a second harmonic dispersion interferometer configured with reflective-beam expanders.

    The Review of scientific instruments·2024
    Same author

    Measurement of 2D density profiles using a second-harmonic, dispersion interferometer.

    The Review of scientific instruments·2023
    Same author

    Partial resolution of acute ascending motor polyneuropathy after enucleation of an eye with metastatic melanoma.

    The British journal of ophthalmology·2004
    Same author

    The AJO: electronic augmentation on the Internet.

    American journal of ophthalmology·2002
    Same author

    Extrascleral extension of a choroidal melanoma after argon photocoagulation and transpupillary thermotherapy.

    The British journal of ophthalmology·2002
    Same author

    Clinical Trials Digest on the Internet at AJO.COM: entering a new information age.

    American journal of ophthalmology·2001
    Same journal

    Forging Ahead: The Need for Improved Representation in Academic Ophthalmology.

    American journal of ophthalmology·2026
    Same journal

    Clinical Utility of Ultra-Widefield Swept-Source OCT for Intraocular Tumors: Comparison With Ultrasonography, SD-OCT, and MRI.

    American journal of ophthalmology·2026
    Same journal

    Therapeutic Advances in Corneal Scar management: Topical Treatments, Mesenchymal Cell Therapy and Stromal Transplantation.

    American journal of ophthalmology·2026
    Same journal

    Increased Risk for Ocular Surface Neoplasia in Recipients of Solid Organ Transplant.

    American journal of ophthalmology·2026
    Same journal

    Aflibercept With vs Without Reduced-Fluence Photodynamic Therapy for Polypoidal Choroidal Vasculopathy: Optical Coherence Tomography Angiographic changes from a randomized clinical trial.

    American journal of ophthalmology·2026
    Same journal

    Posterior Segment Risk Factors for Penetrating Keratoplasty Failure.

    American journal of ophthalmology·2026
    See all related articles

    Area of Science:

    • Toxicology
    • Neuro-ophthalmology
    • Occupational Health

    Background:

    • Methyl bromide is a widely used fumigant with known neurotoxic potential.
    • Occupational exposure can lead to significant health consequences, particularly affecting the nervous system and vision.

    Observation:

    • A 32-year-old fumigation assistant presented with systemic symptoms and neuro-ophthalmic manifestations.
    • Clinical signs included elevated serum bromide levels, peripheral paresthesias, and visual impairment.

    Findings:

    • Ocular examination revealed decreased visual acuity, optic nerve pallor, and abnormal visual-evoked responses.
    • Color vision testing showed a severe green defect, and electrooculography was abnormal, while electroretinography remained normal.
    • Serum bromide levels were significantly elevated at 6.6 mg/100 ml.

    Related Experiment Videos

    Implications:

    • This case highlights the severe and potentially persistent neuro-ophthalmic toxicity of methyl bromide.
    • Early diagnosis and management are crucial for individuals with suspected methyl bromide poisoning.
    • This underscores the importance of safety protocols in occupational settings involving fumigant use.