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Subtyping of Campylobacter jejuni ssp. doylei Isolates Using Mass Spectrometry-based PhyloProteomics MSPP
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Complete Genome Sequences of Three Campylobacter jejuni Phage-Propagating Strains
J C Sacher1, E Yee2, C M Szymanski1,3
1Department of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada.
Genome Announcements
|June 16, 2018
Summary
Bacteriophage therapy shows promise for reducing Campylobacter jejuni in livestock. Researchers sequenced three Campylobacter jejuni strains (NCTC 12660, 12661, 12664) that are susceptible to phage infection, aiding phage-host interaction studies.
Area of Science:
- Microbiology
- Genomics
- Veterinary Science
Background:
- Campylobacter jejuni is a significant pathogen in livestock.
- Bacteriophage therapy offers a potential method for controlling C. jejuni populations.
- Understanding phage-host interactions is crucial for effective bacteriophage therapy.
Purpose of the Study:
- To sequence the complete genomes of three C. jejuni strains.
- To identify phage-propagating strains for bacteriophage therapy research.
- To provide genomic data for studying phage-host interactions in C. jejuni.
Main Methods:
- Whole-genome sequencing of bacterial isolates.
- Bioinformatic analysis of genomic data.
- Identification of C. jejuni strains susceptible to phage infection.
Main Results:
- Complete genome sequences for C. jejuni strains NCTC 12660, NCTC 12661, and NCTC 12664 were obtained.
- These strains were confirmed as phage-propagating strains.
- Genomic data provides a foundation for future phage-host interaction studies.
Conclusions:
- The genomic data of these C. jejuni strains are valuable resources.
- This information supports the development of bacteriophage-based control strategies for C. jejuni in livestock.
- Further research into phage-host dynamics can optimize bacteriophage therapy.
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