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Updated: Feb 9, 2026

Quantitative and Qualitative Examination of Particle-particle Interactions Using Colloidal Probe Nanoscopy
Published on: July 18, 2014
Validation of a novel particle isolation procedure using particle doped tissue samples
J Patel1, S Lal1, S P Wilshaw1
1Faculty of Biological Sciences, University of Leeds, UK.
Abstract:
A novel particle isolation method for tissue samples was developed and tested using particle-doped peri-articular tissues from ovine cadavers. This enabled sensitivity of the isolation technique to be established by doping tissue samples of 0.25 g with very low particle volumes of 2.5 µm3 per sample. Image analysis was used to verify that the method caused no changes to particle size or morphologies.
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