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Beauvaria bassiana keratitis
The British Journal of Ophthalmology
|July 1, 1985
Summary
A rare fungal infection, Beauvaria bassiana, caused progressive corneal thinning and perforation in a patient despite initial antibiotic and corticosteroid treatment. This case highlights the importance of considering fungal keratitis in persistent corneal disease.
Area of Science:
- Ophthalmology
- Medical Mycology
- Infectious Diseases
Background:
- Corneal thinning and perforation can result from various factors, including trauma and infection.
- Corticosteroid use can predispose individuals to opportunistic infections.
Observation:
- A 64-year-old male presented with progressive corneal thinning after foreign body removal and treatment with antibiotics and corticosteroids.
- Initial diagnostic efforts failed to identify an infectious agent, and the condition worsened to corneal perforation.
Findings:
- Histopathological examination of the corneal button after penetrating keratoplasty revealed Beauvaria bassiana.
- Culture confirmed the presence of this fungus, identifying it as the causative agent.
Implications:
- This case underscores the potential for Beauvaria bassiana to cause severe keratitis.
- Ophthalmologists should consider fungal etiologies in refractory or progressive corneal ulcers, even after initial negative workups.