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Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography
Published on: January 15, 2013
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All-depth dispersion cancellation in spectral domain optical coherence tomography using numerical intensity
Mikkel Jensen1, Niels Møller Israelsen2, Michael Maria3,4
1Technical University of Denmark, DTU Fotonik, Kongens Lyngby, 2800, Denmark. mikkje@fotonik.dtu.dk.
Scientific Reports
|June 17, 2018
Summary
Intensity correlation optical coherence tomography (IC-OCT) overcomes dispersion issues in ultra-high resolution OCT. This method, using a single detector, images structures through dispersive materials, challenging previous resolution enhancement claims.
Area of Science:
- Biomedical Optics
- Optical Coherence Tomography
- Metrology
Background:
- Ultra-high resolution optical coherence tomography (UHR-OCT) requires group velocity dispersion (GVD) correction to achieve theoretical resolution limits.
- Existing methods for dispersion compensation, like balanced detection, are experimentally complex.
- Even-order dispersion effects pose a significant challenge in UHR-OCT imaging.
Purpose of the Study:
- To demonstrate intensity correlation spectral domain UHR-OCT (IC-SD-OCT) using a single detector.
- To address and overcome inherent artifacts in IC-SD-OCT, namely cross-term ghost images and reduced axial range.
- To evaluate the performance of IC-SD-OCT in imaging through strongly dispersive materials and to clarify its resolution enhancement capabilities.
Main Methods:
- Implementation of intensity correlation (IC) processing within a conventional spectral domain (SD) UHR-OCT system.
- Application of a generic artifact reduction algorithm and analytic interferograms to mitigate ghost images and extend the axial range.
- Comparative imaging of spatial structures behind a silicon wafer using IC-SD-OCT and conventional SD-OCT.
Main Results:
- Successful demonstration of IC-SD-OCT with a single detector, eliminating the need for balanced detection.
- Removal of cross-term ghost images and restoration of the full axial range using artifact reduction techniques.
- Superior imaging of structures behind a silicon wafer, showcasing IC-SD-OCT's capability in highly dispersive media.
- Clarification that the perceived resolution enhancement in IC-OCT is an artifact of signal processing, not an intrinsic improvement.
Conclusions:
- IC-SD-OCT offers a simplified and effective approach to dispersion compensation in UHR-OCT.
- Artifact reduction techniques are crucial for realizing the full potential of IC-SD-OCT.
- The study clarifies that IC-SD-OCT does not intrinsically offer higher resolution than conventional SD-OCT but provides superior imaging in dispersive environments.
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