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Two distinctive transforming DNA regions on the canine adenovirus type 1 genome

T Yamashita, C S Ren, K Yoshida

Japanese Journal of Cancer Research : Gann

|June 1, 1985

Abstract:

By transfecting cloned DNA fragments of canine adenovirus type 1, a novel transforming region of mammalian adenovirus was demonstrated inside the viral genome. Besides the left-end SmaI-D fragment (left 17.2%), an internally located SmaI-E fragment (17.2-28.7%) of canine adenovirus type 1 was found to transform primary rat kidney cells.

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