Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Polymers02:34

Polymers

41.1K
The word polymer is derived from the Greek words “poly” which means “many” and “mer” which means “parts”. Polymers are long chains of molecules composed of repeating units of smaller molecules, known as monomers. They either occur naturally, such as DNA and proteins, or can be constructed synthetically, like plastics. They have varied structural characteristics, such as linear chains, branched chains, or complex networks, that contribute to the...
41.1K
Polymers02:34

Polymers

23.3K
23.3K
Drug Delivery: Overview01:16

Drug Delivery: Overview

891
The selection of a drug's delivery route depends upon its physicochemical properties, including lipid or water solubility and ionization, as well as the therapeutic requirement, such as immediate or sustained effect. These routes can be divided into three primary categories: enteral, parenteral, and topical.
Enteral delivery involves administering drugs directly through swallowing, sublingual placement, or buccal application. Orally administered drugs predominantly navigate the...
891
Drug Delivery: Enteral Route01:18

Drug Delivery: Enteral Route

1.8K
The enteral drug administration involves three primary routes: oral, sublingual, and buccal. Oral ingestion is the most prevalent, safe, economical, and convenient method for drug administration. However, it has certain drawbacks, including limited absorption due to the drug's low water solubility or poor membrane permeability, possible emesis from GI mucosa irritation, destruction of drugs by digestive enzymes or low gastric pH, and irregular absorption along with food or other drugs.
1.8K
Drug Delivery: Parenteral Route01:29

Drug Delivery: Parenteral Route

1.8K
The parenteral route is a critical method of drug administration. It delivers compounds directly into the systemic circulation and bypasses the gastrointestinal tract. This approach is particularly advantageous for drugs that exhibit poor absorption or instability when administered orally.
There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...
1.8K
Drug Delivery: Miscellaneous Routes01:22

Drug Delivery: Miscellaneous Routes

836
Drug delivery methods like oral inhalation, nasal sprays, transdermal patches, eye drops, intravitreal injection,  and rectal administration provide localized effects with reduced toxicity.
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs...
836

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Recyclable Photopolymers for Sustainable 3D Printing.

Polymer science & technology (Washington, D.C.)·2026
Same author

Sulfur-Substituted SAMs Induce Pb─S Antibonding Hybridization for Efficient and Durable Perovskite-Silicon Tandems.

Advanced materials (Deerfield Beach, Fla.)·2026
Same author

Multi-Field Synergy for Orchestrating Filler Angles in Polyimide Aerogels with Switchable Electromagnetic Interference Shielding.

Advanced materials (Deerfield Beach, Fla.)·2026
Same author

Polyrotaxane-Assembled Semi-Interpenetrating Polymer Electrolytes Enabling High-Voltage Lithium Metal Batteries.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same author

Accelerated Carrier Kinetics in Hollow Cubic Mott-Schottky CoFe@carbon Composites for High-Efficiency Broadband Electromagnetic Wave Absorption.

Small (Weinheim an der Bergstrasse, Germany)·2025
Same author

<i>ortho</i>-C-O arylation of aromatic amides with Grignard reagents through the Meyers reaction.

Organic & biomolecular chemistry·2025

Related Experiment Video

Updated: Feb 8, 2026

Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications
09:39

Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications

Published on: February 7, 2021

8.9K

Hyperbranched Polymers with Controllable Topologies for Drug Delivery.

Qingfu Ban1, Wen Sun2,3, Jie Kong1

  • 1MOE Key Laboratory of Materials Physics and Chemistry in Extraordinary Conditions, Shaanxi Key Laboratory of Macromolecular Science and Technology, School of Science, Northwestern Polytechnical University, Xi'an, 710072, China.

Chemistry, an Asian Journal
|June 19, 2018
PubMed
Summary

Hyperbranched polymers (HPs) offer advanced drug delivery solutions due to their unique structure for drug encapsulation and conjugation. Their scalable synthesis makes them ideal for biomedical applications, enhancing therapeutic efficacy.

Keywords:
drug conjugationdrug deliverynanocarrierspolymerstopology construction

More Related Videos

Synthesis of Functionalized 10-nm Polymer-coated Gold Particles for Endothelium Targeting and Drug Delivery
10:38

Synthesis of Functionalized 10-nm Polymer-coated Gold Particles for Endothelium Targeting and Drug Delivery

Published on: January 15, 2018

13.1K
Modeling and Simulations of Olfactory Drug Delivery with Passive and Active Controls of Nasally Inhaled Pharmaceutical Aerosols
15:04

Modeling and Simulations of Olfactory Drug Delivery with Passive and Active Controls of Nasally Inhaled Pharmaceutical Aerosols

Published on: May 20, 2016

11.4K

Related Experiment Videos

Last Updated: Feb 8, 2026

Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications
09:39

Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications

Published on: February 7, 2021

8.9K
Synthesis of Functionalized 10-nm Polymer-coated Gold Particles for Endothelium Targeting and Drug Delivery
10:38

Synthesis of Functionalized 10-nm Polymer-coated Gold Particles for Endothelium Targeting and Drug Delivery

Published on: January 15, 2018

13.1K
Modeling and Simulations of Olfactory Drug Delivery with Passive and Active Controls of Nasally Inhaled Pharmaceutical Aerosols
15:04

Modeling and Simulations of Olfactory Drug Delivery with Passive and Active Controls of Nasally Inhaled Pharmaceutical Aerosols

Published on: May 20, 2016

11.4K

Area of Science:

  • Polymer Chemistry
  • Materials Science
  • Biomedical Engineering

Background:

  • Hyperbranched polymers (HPs) possess a unique, highly branched topology.
  • This structure provides abundant intramolecular cavities and terminal groups.
  • These features are advantageous for drug encapsulation and conjugation.

Purpose of the Study:

  • To review synthesis methods for hyperbranched polymers with controllable topologies.
  • To discuss the application of HPs in drug delivery, including encapsulation and conjugation.
  • To highlight the potential of HPs for advanced drug delivery systems.

Main Methods:

  • Overview of diverse synthesis strategies for HPs.
  • Discussion of drug encapsulation techniques utilizing HPs.
  • Exploration of drug conjugation methods with HPs.

Main Results:

  • Various methods allow for the synthesis of HPs with tunable architectures.
  • HPs effectively encapsulate and conjugate a wide range of therapeutic agents.
  • The branched structure of HPs facilitates efficient drug loading and release.

Conclusions:

  • Hyperbranched polymers are versatile platforms for drug delivery.
  • Controllable synthesis enables tailored HP architectures for specific biomedical needs.
  • HPs show significant promise for developing next-generation drug delivery systems.