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Pharmacological treatment of alcohol use disorder. Scientific evidence
Fabio Attilia1, Roberta Perciballi1, Claudia Rotondo1
1Centro di Riferimento Alcologico della Regione Lazio (CRARL), Sapienza University of Rome, Italy.
Abstract:
Pharmacological treatment of alcohol use disorder represents an essential core of the therapeutic project in a multidisciplinary approach. While non-drug treatment is evolving, from a medical perspective few pharmacotherapies are available; in particular acamprosate, naltrexone and more recently nalmefene among anticraving drugs, disulfiram as an antidipsotropic medication. New studies are focusing on off-label drugs. Moreover, scientific evidence has to support any therapeutic indication which should be tailored on patient needs and comorbidity by considering the individual bio-psycho-social profile. Follow-up is essential in order to assess patient compliance to treatment and monitoring outcomes.
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