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Updated: Feb 8, 2026

Transcutaneous Microcirculatory Imaging in Preterm Neonates
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Frequency and duration of phototherapy in preterm infants <35 weeks gestation

Devashis Mukherjee1, Mary Coffey2, M Jeffrey Maisels3

  • 1Beaumont Children's Hospital and Department of Pediatrics, Oakland University William Beaumont School of Medicine, Royal Oak, MI, USA.

Journal of Perinatology : Official Journal of the California Perinatal Association
|June 20, 2018
PubMed

Insights

Phototherapy use is high in premature infants (23-34 weeks gestation), especially for those with lower gestational ages. This neonatal intensive care unit (NICU) practice appears to exceed international norms.

Area of Science:

  • Neonatalogy
  • Pediatrics
  • Perinatology

Background:

  • Phototherapy (PT) is a common treatment for hyperbilirubinemia in preterm infants.
  • Guidelines for PT initiation and duration vary, potentially impacting usage patterns.

Purpose of the Study:

  • To assess the frequency, age at initiation, and duration of PT use in preterm infants (23 0/7 to 34 6/7 weeks gestation).
  • To analyze PT utilization trends over time in two neonatal intensive care units (NICUs).

Main Methods:

  • Retrospective chart review of infants born between 23 0/7 and 34 6/7 weeks gestation admitted to two NICUs from January 2009 to September 2015.
  • Calculation of PT proportion and total duration of exposure.

Main Results:

  • 81.8% of eligible infants received PT, with usage inversely related to gestational age (GA) and birthweight.
  • PT initiation criteria including GA led to increased usage.
  • Median PT duration was 50 hours overall, and 74 hours for the lowest GA group.

Conclusions:

  • US consensus guidelines may have increased PT use in these NICUs.
  • PT utilization in these NICUs is considerably more frequent and longer in duration compared to Norwegian studies.
Abstract

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