Related Experiment Video
Updated: Feb 8, 2026
10:28
Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT
Published on: January 22, 2018
11.6K
Uterine Corpus Metastasis From Rectal Adenocarcinoma Detected Using 18F-FDG PET/CT
Hongxi Wang1, Minggang Su1, Futao Cui1
1From the Department of Nuclear Medicine, West China Hospital, and.
Clinical Nuclear Medicine
|June 20, 2018
Summary
We present a rare case of rectal cancer spreading to the uterus, identified using F-FDG PET/CT imaging. This advanced imaging technique helped confirm uterine metastasis in a patient with previously unremarkable ultrasound results.
Area of Science:
- Oncology
- Medical Imaging
- Gynecologic Oncology
Background:
- Rectal adenocarcinoma is a common malignancy with established treatment protocols.
- Metastasis from rectal cancer typically occurs in the liver, lungs, and peritoneum.
- Uterine corpus metastasis from rectal adenocarcinoma is an exceptionally rare event.
Observation:
- A 47-year-old woman, 3 years post-treatment for rectal adenocarcinoma, presented with lower abdominal pain and elevated tumor markers.
- Initial ultrasonography revealed unremarkable findings in the pelvic region.
- Fluorine-18 fluorodeoxyglucose Positron Emission Tomography/Computed Tomography (F-FDG PET/CT) was performed for further investigation.
Findings:
- The F-FDG PET/CT scan demonstrated intense metabolic activity (F-FDG avidity) within the myometrium of the uterine corpus.
- This finding raised suspicion for metastatic disease in the uterus.
- Subsequent Magnetic Resonance Imaging (MRI) and diagnostic curettage with histopathological analysis confirmed uterine metastasis originating from the rectal adenocarcinoma.
Implications:
- This case highlights the importance of considering rare metastatic patterns in cancer follow-up.
- F-FDG PET/CT can be a valuable tool in detecting unusual sites of metastasis when conventional imaging is inconclusive.
- The findings underscore the need for comprehensive diagnostic workup in patients with unexplained symptoms and elevated tumor markers, irrespective of prior treatment status.
Related Concept Videos
01:16Uterine Tubes
2.4K
The uterine or fallopian tubes function as the conduit through which oocytes travel from the ovaries to the uterus. Each fallopian tube measures approximately 10 to 13 cm long and is anatomically divided into the infundibulum, ampulla, isthmus, and interstitial part (or intramural segment). The infundibulum is characterized by its funnel shape and features extensions called fimbriae which reach towards the peritoneal cavity. These fimbriae play a critical role during ovulation as they extend...
2.4K
02:30Metastasis
6.6K
Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
6.6K
01:27Assessing Body Temperature - Rectal
12.5K
Rectal temperature measurement is considered the most precise method for assessing core body temperature and typically registers higher than oral temperature. For adults, the rectal thermometer should be inserted 1 to 1.5 inches into the rectum to obtain the most accurate reading.
Follow these steps for rectal temperature assessment:
Step 1: Perform hand hygiene and don clean gloves to prevent cross-infection.
Step 2: Position the patient in a side-lying position to better visualize the rectal...
Follow these steps for rectal temperature assessment:
Step 1: Perform hand hygiene and don clean gloves to prevent cross-infection.
Step 2: Position the patient in a side-lying position to better visualize the rectal...
12.5K
01:30Radiological Investigation I: X-ray and CT
1.2K
Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and...
1.2K
01:14Imaging Studies I: CT and MRI
907
Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
907
01:28Imaging Studies for Cardiovascular System V: CT
375
Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
375