Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Genomics02:02

Genomics

40.8K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
40.8K
Genomic Imprinting and Inheritance02:30

Genomic Imprinting and Inheritance

37.2K
Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
37.2K
Genome Size and the Evolution of New Genes03:21

Genome Size and the Evolution of New Genes

9.2K
While every living organism has a genome of some kind (be it RNA, or DNA), there is considerable variation in the sizes of these blueprints. One major factor that impacts genome size is whether the organism is prokaryotic or eukaryotic. In prokaryotes, the genome contains little to no non-coding sequence, such that genes are tightly clustered in groups or operons sequentially along the chromosome. Conversely, the genes in eukaryotes are punctuated by long stretches of non-coding sequence.
9.2K
Comparing Mitochondrial, Chloroplast, and Prokaryotic Genomes02:16

Comparing Mitochondrial, Chloroplast, and Prokaryotic Genomes

16.5K
The present-day mitochondrial and chloroplast genomes have retained some of the characteristics of their ancestral prokaryotes and also have acquired new attributes during their evolution within eukaryotic cells. Like prokaryotic genomes, mitochondrial and chloroplast genomes neither bind with histone-like proteins nor show complex packaging into chromosome-like structures, as observed in eukaryotes. Unlike mitotic cell divisions observed in eukaryotic cells, mitochondria and chloroplasts...
16.5K
Defenses Against Pathogens and Herbivores02:26

Defenses Against Pathogens and Herbivores

29.6K
Plants present a rich source of nutrients for many organisms, making it a target for herbivores and infectious agents. Plants, though lacking a proper immune system, have developed an array of constitutive and inducible defenses to fend off these attacks.
29.6K
Defense Against Bacterial Pathogens01:31

Defense Against Bacterial Pathogens

2.9K
The human immune system is a complex network of cells, tissues, and organs that work together to defend the body against bacterial infections. It consists of various immune cells, each playing a specific role in the defense mechanism.
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
2.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ball milling-MnO<sub>2</sub> enables viable straw blanket production via lignin depolymerization.

Bioresource technology·2026
Same author

Adsorption-mediated efficient glucose electrooxidation on transition metal aerogels for biomass upgradation.

Chemical science·2025
Same author

HPV specificity and multiple infections and association with cervical cytology in Chongqing, China: a cross-sectional study.

BMC infectious diseases·2024
Same author

Prognostic factors in children and adolescents with differentiated thyroid cancer treated with total thyroidectomy and radioiodine therapy: a retrospective two-center study from China.

Frontiers in endocrinology·2024
Same author

Efficacy and safety of variceal embolization for primary prophylaxis in cirrhosis patients with challenges in standard treatments: preliminary results.

Frontiers in medicine·2024
Same author

Therapeutic Potential of Mesenchymal Stem Cell-Derived Exosomes as Nanomedicine for Peripheral Nerve Injury.

International journal of molecular sciences·2024

Related Experiment Video

Updated: Feb 8, 2026

Metagenomic Analysis of Silage
08:43

Metagenomic Analysis of Silage

Published on: January 13, 2017

19.1K

MPD: a pathogen genome and metagenome database.

Tingting Zhang1,2, Jiaojiao Miao1,2, Na Han1,2

  • 1State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China.

Database : the Journal of Biological Databases and Curation
|June 20, 2018
PubMed
Summary
This summary is machine-generated.

The Mypathogen database (MPD) offers a solution for managing and sharing vast bacterial genomics data. This resource supports researchers by providing access to microbial genomes and metagenomes for enhanced disease analysis.

More Related Videos

Purifying the Impure: Sequencing Metagenomes and Metatranscriptomes from Complex Animal-associated Samples
11:23

Purifying the Impure: Sequencing Metagenomes and Metatranscriptomes from Complex Animal-associated Samples

Published on: December 22, 2014

37.7K
Large-Scale Screens of Metagenomic Libraries
16:05

Large-Scale Screens of Metagenomic Libraries

Published on: May 28, 2007

9.2K

Related Experiment Videos

Last Updated: Feb 8, 2026

Metagenomic Analysis of Silage
08:43

Metagenomic Analysis of Silage

Published on: January 13, 2017

19.1K
Purifying the Impure: Sequencing Metagenomes and Metatranscriptomes from Complex Animal-associated Samples
11:23

Purifying the Impure: Sequencing Metagenomes and Metatranscriptomes from Complex Animal-associated Samples

Published on: December 22, 2014

37.7K
Large-Scale Screens of Metagenomic Libraries
16:05

Large-Scale Screens of Metagenomic Libraries

Published on: May 28, 2007

9.2K

Area of Science:

  • Microbiology
  • Genomics
  • Bioinformatics

Background:

  • High-throughput sequencing generates massive bacterial genome data, posing storage and management challenges.
  • Efficiently managing and sharing this data is crucial for advancing bacterial research and public health initiatives.

Purpose of the Study:

  • To introduce the Mypathogen database (MPD), a novel resource for accessing, storing, and sharing bacterial genomics and metagenomics data.
  • To provide a centralized platform that facilitates data management and collaboration among research groups and organizations.

Main Methods:

  • Development of the Mypathogen database (MPD) to integrate and manage microbial genomics and metagenomics datasets.
  • Implementation of a user-friendly local client tool for efficient transmission of large sequencing data.

Main Results:

  • The MPD currently houses data for 6,604 genera, 11,071 species, and 41,906 strains of pathogenic microbial genomes.
  • It also includes 28,816 metagenomic samples from various sources (host, air, water).
  • The database functions as a management system for statistical and storage data, enabling inter-organizational data sharing.

Conclusions:

  • The MPD is a valuable tool for genomic research, particularly for clinical, epidemiological, and public health studies.
  • It is expected to significantly contribute to the understanding of pathogenic bacteria genomes and metagenomes.
  • The database promotes data accessibility and collaborative research in microbial genomics.