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Treating Pediatric Hydrocephalus at the Neurosurgery Education and Development Institute: The Reality in the Zanzibar
Andreas Leidinger1, Jose Piquer2, Eliana E Kim3
1Neurosurgery Education and Development (NED) Foundation, Valencia, Spain; Neurosurgery Education and Development (NED) Institute, Mnazi Mmoja Hospital, Stonetown, Tanzania.
Insights
Pediatric hydrocephalus in Zanzibar presents similar causes and outcomes to other African regions. Postinfectious hydrocephalus is a significant factor and may be preventable.
Area of Science:
- Neuroscience
- Pediatric Neurosurgery
- Epidemiology
Background:
- Pediatric hydrocephalus poses a significant health burden in East Africa, with approximately 6000 new cases annually.
- This study focuses on the epidemiology and surgical outcomes of pediatric hydrocephalus in Zanzibar's sole neurosurgical center.
Purpose of the Study:
- To describe the epidemiological characteristics of pediatric hydrocephalus in Zanzibar.
- To evaluate the surgical outcomes and complication rates for pediatric hydrocephalus patients in Zanzibar.
Main Methods:
- Prospective data collection from December 2016 to December 2017.
- Gathered information on demographics, maternal health, imaging, surgical procedures, and complications for 63 hydrocephalus patients.
Main Results:
- The study included 63 pediatric patients with hydrocephalus; the most common etiology was postinfectious (39.7%).
- Surgical interventions included 7 endoscopic third ventriculostomies and 40 ventriculoperitoneal shunts, with a 12.5% complication rate at follow-up.
- Presenting symptoms included signs of infection (46.0%), congenital abnormalities (20.6%), and seizures (20.6%).
Conclusions:
- Hydrocephalus in Zanzibar shares etiological and outcome similarities with other African settings.
- Postinfectious hydrocephalus is a major contributor and warrants further investigation for potential prevention strategies.
Background:
Pediatric hydrocephalus is a health burden for East African countries, with an estimated incidence of 6000 new cases per year. The objective of this study is to describe the epidemiology and surgical outcomes of patients treated for pediatric hydrocephalus in the single neurosurgical center of Zanzibar.
Methods:
From December 2016 to December 2017, we prospectively collected data on all patients admitted with the diagnosis of hydrocephalus. Information was gathered regarding demographics, maternal health, preoperative imaging, surgical procedures, and postsurgical complications.
Results:
We collected data on 63 patients. Average age was 203 days, and gender was 49.2% female and 50.8% male. All mothers of patients attended an antenatal clinic for routine screening during pregnancy. Folic acid prophylaxis was used by 9.5% of the mothers during pregnancy. At the first visit, 46.0% of patients presented with signs of infection, 20.6% with congenital abnormalities, and 20.6% with seizures. Regarding etiology of hydrocephalus, 22.2% of all cases were uncertain; 20.6% were associated with neural tube defects; 39.7% were postinfectious hydrocephalus; 3.2% were aqueduct stenosis; 4.8% were associated with brain tumor; and 9.6% were malformative. We performed 7 endoscopic third ventriculostomies and placed 40 ventriculoperitoneal shunts. The complication rate at follow-up was 12.5%.
Conclusions:
It seems that hydrocephalus in Zanzibar has similar causes, progression, and complication rates to previous reports from other African hospitals. Further studies of postinfectious hydrocephalus need to be conducted because recent findings suggest that it is a potentially preventable cause of the disease.
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