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Abstract:
The leading symptom of dyserythropoiesis is an increased, ineffective erythropoiesis with characteristic morphological and functional features. The molecular background of the disturbances is unknown. There are similar structural and biochemical characteristics with different etiologic factors. In addition to rare, congenital forms acquired forms are observed frequently. A causal therapy is only known in deficiency and toxic states. There is an increased risk of transfusion hypersiderosis for the rest of patients with dyserythropoiesis. Among the acquired forms frequently premalignant diseases and tumours are found.