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Published on: October 16, 2019
Comparing Approaches to Mobile Depression Assessment for Measurement-Based Care: Prospective Study
Amy M Bauer1, Scott A Baldwin2, Joaquin A Anguera3
1Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, United States.
Daily symptom monitoring using the Patient Health Questionnaire-2 (PHQ-2) is a reliable proxy for the Patient Health Questionnaire-9 (PHQ-9). These mobile health tools effectively predict depression outcomes and disability.
Area of Science:
- Psychiatry and Mental Health
- Digital Health
- Clinical Research
Background:
- Routine symptom monitoring is recommended for measurement-based care in depression.
- Remote patient monitoring via mobile health tools is increasing.
- The reliability of daily depression symptom ratings requires further investigation.
Purpose of the Study:
- To assess the association between daily Patient Health Questionnaire-2 (PHQ-2) ratings and the Patient Health Questionnaire-9 (PHQ-9).
- To compare the predictive validity of daily PHQ-2 and PHQ-9 for patient outcomes.
- To evaluate mobile health tools for depression assessment.
Main Methods:
- 547 individuals completed smartphone-based measures, including daily PHQ-2 and weekly PHQ-9.
- Multilevel factor analyses assessed the reliability of daily PHQ-2 ratings (weeks 2-4).
- Regression models predicted week 8 depressive symptoms and disability using daily PHQ-2 and PHQ-9 data.
Main Results:
- Daily PHQ-2 and PHQ-9 showed high reliability (0.80-0.88) and correlation (r=0.80).
- Findings were consistent across diverse demographic groups.
- Both daily PHQ-2 and PHQ-9 effectively predicted week 8 disability and depressive symptoms.
Conclusions:
- Daily PHQ-2 serves as a reliable proxy for PHQ-9 in depression assessment.
- Mobile assessment methods provide valid and reliable tools for depression research and care.
- Leveraging daily mobile assessments can enhance measurement-based depression care.
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