A cohort study on risk factors for preterm births in rural Gujarat

Poonam Trivedi1, Deepak Saxena2, Tapasvi Puwar3

  • 1Senior Research Assistant, Indian Institute of Public Health, Gandhinagar, Gujarat, India.

Insights

Preterm birth (PTB) affects infant mortality globally. This study identified periodontal disease, longer sleep duration, and sexual activity during pregnancy as significant risk factors for PTB in India.

Area of Science:

  • Obstetrics and Gynecology
  • Neonatal Health
  • Public Health Research

Background:

  • Preterm birth (PTB) is a major cause of neonatal and under-five mortality in India and globally.
  • PTB contributes to significant short- and long-term infant morbidities.
  • Many PTB risk factors remain unexplained, necessitating community-based research in high-burden regions like India.

Purpose of the Study:

  • To investigate and identify various risk factors associated with preterm birth (PTB).

Main Methods:

  • A cohort of 1977 antenatal mothers was enrolled and followed in Gujarat, India.
  • Data on pregnancy outcomes and potential risk factors were collected using structured questionnaires.
  • A hierarchical regression model was employed to analyze risk factors for PTB.

Main Results:

  • The study observed a 9% proportion of preterm births (PTBs) within the enrolled cohort.
  • Significant risk factors identified included periodontal disease, prolonged sleep duration, and sexual activity during any trimester.
  • These findings highlight specific, modifiable factors contributing to PTB.

Conclusions:

  • There is an urgent need for enhanced, evidence-based interventions to prevent PTB.
  • Routine antenatal care should include screening for oral hygiene due to the link with PTB.
  • Promoting good oral hygiene practices for pregnant women is recommended.
Abstract

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