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Published on: December 6, 2016
Clinical Predictors of Pediatric Obstructive Sleep Apnea Syndrome
Chi-Chih Lai1, Pei-Wen Lin2,3, Hsin-Ching Lin1,2
11 Department of Otolaryngology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung Chang Gung Children Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Insights
A new model using snoring, nasal obstruction, and BMI z-score can predict pediatric obstructive sleep apnea/hypopnea syndrome (OSAS). This simple tool aids physicians in identifying children needing further polysomnography (PSG) diagnostics and treatment.
Area of Science:
- Pediatric Pulmonology
- Sleep Medicine
- Clinical Diagnostics
Background:
- Pediatric obstructive sleep apnea/hypopnea syndrome (OSAS) diagnosis relies on polysomnography (PSG).
- Predictive clinical models are needed for early screening and efficient diagnosis.
Purpose of the Study:
- To develop a predictive model for pediatric OSAS using clinical and physical factors.
- To identify reliable, noninvasive predictors of the apnea/hypopnea index (AHI).
Main Methods:
- Evaluated anthropometric measurements (BMI z-score), tonsil size, and Friedman tongue position.
- Assessed clinical symptoms: snoring visual analog scale (VAS), nasal obstruction, and mouth breathing.
- Utilized stepwise multiple linear regression for model development.
Main Results:
- Snoring VAS, nasal obstruction, mouth breathing, and BMI z-score correlated significantly with AHI/h.
- A predictive model was established: Pediatric AHI = 0.108 + 0.103 snoring VAS + 0.894 nasal obstruction + 0.207 BMI z-score.
- The model demonstrated statistical significance (F = 4.06, P = .01).
Conclusions:
- A noninvasive screening tool for pediatric OSAS was developed.
- The model effectively predicts AHI using simple clinical measures.
- This tool can guide physicians toward necessary PSG diagnostics and treatment.
Objective:
To develop an adequate model using reliable clinical and physical factors to predict pediatric obstructive sleep apnea/hypopnea syndrome (OSAS).
Methods:
Complete anthropometric measurements including BMI z score, tonsil size grading, and updated Friedman tongue position (uFTP) were evaluated. Subjective assessments of clinical symptoms/signs, including snoring visual analog scale (VAS), nasal obstruction, and mouth breathing, were recorded.
Results:
Eighty-eight children (57 boys and 31 girls, mean age = 9.0 years) were confirmed to have OSAS by comprehensive polysomnography (PSG). When the aforementioned variables were analyzed individually, the results indicated that snoring VAS, nasal obstruction, mouth breathing, and BMI z score were reliable predictors of apnea/hypopnea index (AHI/h) values (correlation coefficient r = 0.386, P < .001; r = 0.416, P < .001; r = 0.255, P = .02; and r = 0.243, P = .02, respectively). When all significant factors were included in the stepwise multiple linear regression analysis, the final predictive model is: Pediatric AHI = 0.108 + 0.103 snoring VAS + 0.894 nasal obstruction + 0.207 BMI z score ( F = 4.06, P = .01).
Conclusion:
The proposed noninvasive, simple, inexpensive, and easy to perform screening tool could be used to predict pediatric OSAS. An abnormal calculated AHI may prompt clinical physicians to conduct further PSG diagnostics and treatment.
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