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Updated: Feb 8, 2026

Randomized, Triple-Blind, and Parallel-Controlled Trial of Transcranial Direct Current Stimulation for Cognitive Rehabilitation after Stroke
Published on: June 6, 2025
Dual Transcranial Direct Current Stimulation for Poststroke Dysphagia: A Randomized Controlled Trial.
Valeria Pingue1, Alberto Priori2, Alberto Malovini1
11 IRCCS ICS Maugeri, Pavia, Italy.
Dual transcranial direct current stimulation (tDCS) did not significantly improve early poststroke dysphagia recovery. However, patients without nasogastric tubes showed better outcomes with tDCS, suggesting potential benefits for specific patient groups.
Area of Science:
- Neuroscience
- Rehabilitation Medicine
- Clinical Neurology
Background:
- Poststroke dysphagia presents significant morbidity and high healthcare costs.
- Effective early rehabilitation strategies for poststroke dysphagia are crucial.
Purpose of the Study:
- To assess the efficacy of anodal/cathodal transcranial direct current stimulation (tDCS) in improving dysphagia during early post-stroke rehabilitation.
- To compare dual tDCS with sham stimulation for poststroke swallowing dysfunction.
Main Methods:
- 40 patients with poststroke dysphagia were randomized to receive 10 sessions of dual tDCS or sham stimulation during swallowing exercises.
- Swallowing function was quantitatively assessed using the Dysphagia Outcome and Severity Scale (DOSS) before and after treatment.
Main Results:
- While a higher percentage of patients in the tDCS group showed improvement, the difference was not statistically significant compared to the sham group.
- A significant improvement was observed in the subgroup of patients not requiring a nasogastric tube receiving tDCS compared to sham (P = .01).
Conclusions:
- Dual tDCS applied in the early rehabilitation phase does not significantly enhance recovery from poststroke dysphagia overall.
- Early dual tDCS may offer benefits for specific patient subgroups, such as those without nasogastric tube dependence.
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