Related Experiment Video

Updated: Feb 8, 2026

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
14:14

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement

Published on: December 11, 2017

14.7K

Coronary Revascularisation in Transcatheter Aortic Valve Implantation Candidates: Why, Who, When?

Davide Cao1,2, Mauro Chiarito1,2, Paolo Pagnotta1,2

  • 1Department of Biomedical Sciences, Humanitas University, Pieve Emanuele-Milan Italy.

Interventional Cardiology (London, England)
|June 22, 2018
PubMed

Insights

Coronary artery disease (CAD) management during transcatheter aortic valve implantation (TAVI) remains debated. This review examines the role of coronary revascularization in TAVI patients, contrasting it with surgical valve replacement guidelines.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Cardiac Surgery

Background:

  • Coronary artery disease (CAD) and aortic stenosis (AS) often coexist, impacting patient prognosis.
  • CAD significantly worsens outcomes in patients undergoing surgical aortic valve replacement (SAVR).
  • Guidelines recommend coronary revascularization for significant CAD in SAVR patients.

Purpose of the Study:

  • To review the current evidence on coronary revascularization in patients undergoing transcatheter aortic valve implantation (TAVI).
  • To discuss the ongoing debate regarding the management of concomitant CAD in TAVI candidates.
  • To provide an overview of the role of coronary revascularization in the TAVI population.

Main Methods:

  • Literature review of studies investigating CAD management in TAVI patients.
  • Analysis of current guidelines for CAD management in SAVR.
  • Synthesis of evidence regarding the impact of coronary revascularization on TAVI outcomes.

Main Results:

  • The role of coronary revascularization in TAVI patients is less defined than in SAVR.
  • Evidence regarding the benefit of routine revascularization in TAVI patients is still evolving.
  • Optimal management strategies for concomitant CAD in TAVI are under active investigation.

Conclusions:

  • The management of coronary artery disease in patients undergoing transcatheter aortic valve implantation requires careful consideration.
  • Further research is needed to establish definitive guidelines for coronary revascularization in TAVI.
  • Individualized treatment approaches are crucial for patients with concomitant CAD and severe aortic stenosis undergoing TAVI.

Keywords:
Concomitant PCISyntax Scorecoronary artery diseasepercutaneous coronary interventionsevere aortic stenosisstaged PCItranscatheter aortic valve implantation

More Related Videos

Improved Registration of 3D CT Angiography with X-ray Fluoroscopy for Image Fusion During Transcatheter Aortic Valve Implantation06:59

Improved Registration of 3D CT Angiography with X-ray Fluoroscopy for Image Fusion During Transcatheter Aortic Valve Implantation

Published on: June 3, 2018

11.1K
Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots12:17

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Published on: May 21, 2017

11.9K

Related Concept Videos

Heart Valves01:16

Heart Valves

The human heart is a complex organ with an intricate system of valves that regulate blood flow. There are two main types of valves: atrioventricular (AV) valves and semilunar valves.
The AV valves prevent the backflow of blood from the ventricles to the atria during ventricular contraction. These valves function with the assistance of the chordae tendineae and papillary muscles. When the ventricles are relaxed, the chordae tendineae are slack, allowing blood to flow from the atria into the...
12.2K
Coronary Circulation01:21

Coronary Circulation

The heart, an organ critical to survival, gets nourishment not from the blood it pumps but from a separate circulation system known as coronary circulation. This is the shortest circulation in the body and is responsible for supplying the heart with the nutrients it needs to function effectively.
Coronary circulation begins at the base of the aorta, where two main arteries arise—the left and right coronary arteries. These arteries encircle the heart in the coronary sulcus and supply the...
7.4K
Mitral Valve Prolapse I: Introduction01:27

Mitral Valve Prolapse I: Introduction

IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...
570
Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
657
Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
1.2K
Coronary Artery Disease II: Pathophysiology01:26

Coronary Artery Disease II: Pathophysiology

Coronary Artery Disease (CAD) originates from a series of events that impair the function of coronary arteries, the blood vessels responsible for delivering oxygen-rich blood to the heart muscle. The pathophysiology of CAD is closely linked to atherosclerosis, a chronic inflammatory and lipid-driven condition affecting the vascular endothelium.1. Endothelial DamageThe process begins with damage to the vascular endothelium, which serves as a protective barrier between the blood and the vessel...
504