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Updated: Feb 8, 2026

Visualization of Endoplasmic Reticulum Subdomains in Cultured Cells
Published on: February 18, 2014
Oxidative and endoplasmic reticulum stress in respiratory disease
Alice C-H Chen1,2, Lucy Burr3, Michael A McGuckin4
1Diamantina Institute Faculty of Medicine The University of Queensland Brisbane QLD Australia.
Abstract:
Oxidative stress and endoplasmic reticulum (ER) stress are related states that can occur in cells as part of normal physiology but occur frequently in diseases involving inflammation. In this article, we review recent findings relating to the role of oxidative and ER stress in the pathophysiology of acute and chronic nonmalignant diseases of the lung, including infections, cystic fibrosis, idiopathic pulmonary fibrosis and asthma. We also explore the potential of drugs targeting oxidative and ER stress pathways to alleviate disease.
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