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Updated: Oct 7, 2026

Measuring Local Anaphylaxis in Mice
Published on: October 14, 2014
The Benefits of Managing Anaphylaxis at Home
1Department of Pediatrics at the University of Alabama at Birmingham, Division of Allergy and Clinical Immunology, 1601 4th Avenue South, CPP II, Suite 220, Birmingham, AL 35233, USA.
Abstract:
Based on current data, immediate activation of EMS in all cases of anaphylaxis does not provide significant benefit. Instead, the option for home management or a "watchful-waiting" approach allowing for increased patient autonomy in anaphylaxis management and emphasizing prompt epinephrine use at home. In this model, patients are instructed to quickly administer epinephrine and monitor for resolution of symptoms. The option to escalate care is available, but in 90% of cases, symptoms will resolve after one dose of epinephrine, rendering EMS/ED involvement unnecessary. Thus, patients can immediately treat their anaphylaxis from the comfort of home while avoiding complications from delayed epinephrine use.
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