Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Tonsillitis II: Management01:26

Tonsillitis II: Management

439
This lesson will focus on the different treatment options for managing tonsillitis, which typically depend on the cause and severity.
439
Impression Management Techniques I: Managing Appearances01:29

Impression Management Techniques I: Managing Appearances

220
Appearance is a multidimensional aspect of self-presentation that encompasses observable attributes such as clothing, grooming, speech, and nonverbal behavior. These elements are often strategically managed to align with socially constructed expectations in different settings. For instance, individuals tailor their appearance during job interviews, social gatherings, or athletic events to meet the perceived norms of those environments.Contextual Adaptation and Social SignalsThe research...
220
Managing Impressions01:19

Managing Impressions

177
Impression management encompasses individuals' deliberate efforts to shape how others perceive them during social interactions. This behavior is often employed to conform to social norms, secure approval, or pursue specific goals. While it involves selective self-presentation, it is not necessarily deceptive; individuals frequently present authentic aspects of themselves that align with situational demands.Common strategies include:Ingratiation: where individuals use flattery or agreeableness...
177
Management of Insomnia01:19

Management of Insomnia

666
The sleep cycle, an integral part of human health, consists of several stages with distinct characteristics and functions. It begins with a transition from wakefulness to sleep, known as the light sleep phase, followed by the restorative deep sleep phase, essential for physical recovery and growth. The cycle concludes with the Rapid Eye Movement (REM) phase, characterized by high brain activity and vivid dreaming. Insomnia, a prevalent sleep disorder, involves difficulty falling asleep, staying...
666
Cystic Fibrosis: Management01:24

Cystic Fibrosis: Management

546
Cystic fibrosis (CF) is an autosomal recessive disorder that predominantly affects individuals of Northern European descent, occurring at a rate of 1 in 3500. It is caused by a genetic mutation in a gene on chromosome 7, most commonly the ΔF508 mutation, that codes for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. This results in thicker mucus secretions and obstruction pathologies in multiple organs, including the lungs and sinuses.
Sinus disease and chronic...
546
Angina IV: Management01:26

Angina IV: Management

297
IntroductionThe management of angina requires a comprehensive approach that includes pharmacological therapies, medical procedures, and lifestyle modifications.Pharmacological TherapiesAntiplatelet agents, such as aspirin, clopidogrel, prasugrel, and ticagrelor, play a pivotal role in preventing thrombus formation in patients with angina. These medications inhibit platelet aggregation and reduce the likelihood of myocardial infarction and other cardiovascular events.Anticoagulants, including...
297

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Itch, Scratching, and Sleep Mediate the Association between Disease Severity and Quality of Life in Pruritic Dermatoses: A Cross-Sectional Study.

Dermatology and therapy·2026
Same author

Dupilumab treatment restores skin nerve fibre density in patients with moderate-to-severe atopic dermatitis: results from DIFFERENSTAD, an open-label exploratory study.

The British journal of dermatology·2026
Same author

Quick assessment of quality-of-life in itch: An exploratory validation of the 5-item pruritus life quality.

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·2026
Same author

[Chronic prurigo: overview of pathophysiology, diagnosis, and treatment].

Dermatologie (Heidelberg, Germany)·2026
Same author

Evaluation of itch intensity scales in atopic dermatitis: Differential measurement properties and associations with relevant cytokines.

The Journal of investigative dermatology·2026
Same author

Elevated lymphoma risk in patients with chronic pruritus and chronic prurigo.

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·2026
Same journal

The Evidence Is In: Devices and Biologics Reshaping Modern Dermatology.

Dermatologic clinics·2026
Same journal

Energy-Based Devices for Body Contouring.

Dermatologic clinics·2026
Same journal

Microfocused Ultrasound with Visualization for Skin Tightening: Clinical Applications, Safety, and Technical Considerations.

Dermatologic clinics·2026
Same journal

Devices in Onychomycosis: A Status Update.

Dermatologic clinics·2026
Same journal

Acne Laser Devices in Dermatology.

Dermatologic clinics·2026
Same journal

Fractional Laser Therapy for Androgenetic Alopecia: Mechanisms, Clinical Evidence, and Practical Implementation.

Dermatologic clinics·2026
See all related articles

Related Experiment Video

Updated: Feb 8, 2026

The Dyspepsia Educational Tool As a Novel Aid in Dyspepsia Management
06:40

The Dyspepsia Educational Tool As a Novel Aid in Dyspepsia Management

Published on: June 29, 2019

7.1K

Prurigo Nodularis and Its Management.

Claudia Zeidler1, Gil Yosipovitch2, Sonja Ständer1

  • 1Department of Dermatology, Center for Chronic Pruritus, University Hospital Münster, Von- Esmarch-Strasse 58, Münster DE-48149, Germany.

Dermatologic Clinics
|June 23, 2018
PubMed
Summary
This summary is machine-generated.

Prurigo nodularis is a skin condition causing itchy nodules, linked to nerve changes and various underlying health issues. Current treatments include topical therapies, phototherapy, and systemic medications targeting nerve pathways.

Keywords:
Chronic pruritusItchPrurigo nodularisPruritusScratch lesionsTherapy

More Related Videos

Measuring and Mapping Patterns of Soil Erosion and Deposition Related to Soil Carbonate Concentrations Under Agricultural Management
08:09

Measuring and Mapping Patterns of Soil Erosion and Deposition Related to Soil Carbonate Concentrations Under Agricultural Management

Published on: September 12, 2017

12.3K
Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management
06:43

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management

Published on: November 21, 2017

25.0K

Related Experiment Videos

Last Updated: Feb 8, 2026

The Dyspepsia Educational Tool As a Novel Aid in Dyspepsia Management
06:40

The Dyspepsia Educational Tool As a Novel Aid in Dyspepsia Management

Published on: June 29, 2019

7.1K
Measuring and Mapping Patterns of Soil Erosion and Deposition Related to Soil Carbonate Concentrations Under Agricultural Management
08:09

Measuring and Mapping Patterns of Soil Erosion and Deposition Related to Soil Carbonate Concentrations Under Agricultural Management

Published on: September 12, 2017

12.3K
Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management
06:43

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management

Published on: November 21, 2017

25.0K

Area of Science:

  • Dermatology
  • Neurology

Background:

  • Prurigo nodularis is characterized by chronic pruritus and hyperkeratotic, intensely itching nodules.
  • It is associated with diverse dermatologic, systemic, neurologic, or psychiatric conditions.
  • Pathological findings include reduced intraepidermal nerve fiber density and elevated dermal nerve growth factor and neuropeptides.

Purpose of the Study:

  • To review the pathophysiology and therapeutic strategies for prurigo nodularis.
  • To highlight novel therapeutic targets and established treatment modalities.

Main Methods:

  • Literature review of studies on prurigo nodularis pathophysiology and treatment.
  • Analysis of structural and molecular findings in affected skin.
  • Evaluation of current and emerging therapeutic agents.

Main Results:

  • Prurigo nodularis involves nerve fiber abnormalities and neurochemical alterations.
  • Novel therapies targeting neurokinin-1, opioid, and interleukin-31 receptors are under development.
  • Established treatments include topical steroids, capsaicin, phototherapy, and systemic medications.

Conclusions:

  • Prurigo nodularis is a complex condition with significant neurological involvement.
  • Therapeutic approaches are evolving, with a focus on targeting underlying pathomechanisms.
  • A combination of established and novel treatments may offer improved patient outcomes.