[Thermoregulatory effect of beta-adrenoreceptor block in the cold-adapted rat at rest and during exertion]

Inderal does not affect the thermoregulatory system in thermoneutral conditions. Blockade of beta-adrenoreceptors at 6 degrees C decreases the oxygen consumption in cold-acclimated rats and reduces it down to the level of control animals. Cold-acclimated rats have the same level of work hyperthermia at different ambient temperatures (26 degrees C, 6 degrees C) and under inderal injection. Control animals can only the same in warm environment.