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Updated: Feb 8, 2026

Normothermic Ex Situ Heart Perfusion in Working Mode: Assessment of Cardiac Function and Metabolism
Published on: January 12, 2019
Blunt cardiac injury with scintigraphic perfusion-metabolism mismatch
Miki Morikawa1, Akiyoshi Hagiwara2, Taigo Sakamoto3
1Department of Emergency and Critical Care Medicine Juntendo University Urayasu Hospital Urayasu Chiba Japan.
Patient:
A healthy 37-year-old man who bruised his chest with a steel frame developed ventricular fibrillation, pulseless ventricular tachycardia, and temporary torsade de pointes, and was resuscitated with emergency medical treatment. Thallium 201 scintigraphy 7 days later revealed a defect only in a small area of the apex, whereas 123 I-beta-methyl iodophenyl pentadecanoic acid scintigraphy showed defects in a larger area of the apex, ventricular septum, and inferior wall, indicating perfusion-metabolism mismatch. Follow-up dual myocardial scintigraphy on day 49 showed that the scintigraphic defects persisted only at a small area of the apex.
Conclusion:
Blunt external force appeared to have caused perfusion-metabolism mismatch and subsequent life-threatening arrhythmias in this patient.
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