Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Scientific Method03:50

The Scientific Method

67.9K
Chemistry is an empirical science. Scientists often pose questions to understand the chemistry in everyday life and seek answers to these questions. To achieve this, scientists follow a definitive series of steps that together make up the Scientific Method. This approach involves making observations, asking questions, building a hypothesis, conducting experiments, analyzing results, and forming a conclusion. 
67.9K
The Scientific Method01:32

The Scientific Method

269.2K
The scientific method is a detailed, empirical problem-solving process used by biologists and other scientists. This iterative approach involves formulating a question based on observation, developing a testable potential explanation for the observation (called a hypothesis), making and testing predictions based on the hypothesis, and using the findings to create new hypotheses and predictions.
Generally, predictions are tested using carefully-designed experiments. Based on the outcome of these...
269.2K
The Scientific Method02:40

The Scientific Method

65.8K
Research is what makes the difference between facts and opinions. Facts are observable realities, and opinions are personal judgments, conclusions, or attitudes that may or may not be accurate. In the scientific community, facts can be established only using evidence collected through empirical research.
65.8K
Sample Size Calculation01:19

Sample Size Calculation

6.7K
Knowledge of the sample size is the first requirement to conduct random sampling or an experiment. The sample size is the total number of units, observations, or groups (in some cases) used to get the data to estimate a population parameter. As the name suggests, the sample size is that of the sample drawn from the population and differs from the population size.
The sample size for the given experiment or sampling effort is fundamental to any study design. Sample size decides the number of...
6.7K
One-Way ANOVA: Unequal Sample Sizes01:15

One-Way ANOVA: Unequal Sample Sizes

6.8K
One-way ANOVA can be performed on three or more samples of unequal sizes. However, calculations get complicated when sample sizes are not always the same. So, while performing ANOVA with unequal samples size, the following equation is used:
6.8K
One-Way ANOVA: Equal Sample Sizes01:15

One-Way ANOVA: Equal Sample Sizes

4.1K
One-Way ANOVA can be performed on three or more samples with equal or unequal sample sizes. When one-way ANOVA is performed on two datasets with samples of equal sizes, it can be easily observed that the computed F statistic is highly sensitive to the sample mean.
Different sample means can result in different values for the variance estimate: variance between samples. This is because the variance between samples is calculated as the product of the sample size and the variance between the...
4.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Removal of a Fishhook-Shaped Foreign Body in the Bronchus and Literature Review.

Respirology case reports·2026
Same author

Environmental conditions and animal hosts shape the spatial transmission risks of echinococcosis in China.

Acta tropica·2026
Same author

Forecasting influenza activity based on internet retrieval behavior and meteorological data in four megacities of China.

BMC infectious diseases·2026
Same author

A global dataset of spatiotemporal co-occurrence patterns of avian influenza virus-associated migratory birds.

Scientific data·2026
Same author

Mapping the landscape of healthcare-associated infections in China, 2015-2019: a nation-wide observational study.

The Lancet regional health. Western Pacific·2026
Same author

Epidemiological analysis of infectious diseases in older people in China from 2014 to 2022: a population-based study.

The Lancet regional health. Western Pacific·2025

Related Experiment Video

Updated: Feb 8, 2026

Experimental Manipulation of Body Size to Estimate Morphological Scaling Relationships in Drosophila
06:00

Experimental Manipulation of Body Size to Estimate Morphological Scaling Relationships in Drosophila

Published on: October 1, 2011

14.4K

[How to scientifically estimate sample size in physiological research].

Yi-Song Liu1, Chun-Xue Guo1, Wan Hu1

  • 1Consulting Center of Biomedical Statistics, Academy of Military Medical Sciences, Beijing 100850, China.

Zhongguo Ying Yong Sheng Li Xue Za Zhi = Zhongguo Yingyong Shenglixue Zazhi = Chinese Journal of Applied Physiology
|June 23, 2018
PubMed
Summary
This summary is machine-generated.

Accurate sample size estimation is crucial for physiological research. Proper calculation ensures reliable results by meeting statistical premises and using appropriate methods.

Keywords:
multiple comparisonsphysiological researchsample size estimationtwo-sample parallel design

More Related Videos

Leaf Area Index Estimation Using Three Distinct Methods in Pure Deciduous Stands
09:04

Leaf Area Index Estimation Using Three Distinct Methods in Pure Deciduous Stands

Published on: August 29, 2019

14.2K
Sampling for Estimating Frankliniella Species Flower Thrips and Orius Species Predators in Field Experiments
07:13

Sampling for Estimating Frankliniella Species Flower Thrips and Orius Species Predators in Field Experiments

Published on: July 17, 2019

9.8K

Related Experiment Videos

Last Updated: Feb 8, 2026

Experimental Manipulation of Body Size to Estimate Morphological Scaling Relationships in Drosophila
06:00

Experimental Manipulation of Body Size to Estimate Morphological Scaling Relationships in Drosophila

Published on: October 1, 2011

14.4K
Leaf Area Index Estimation Using Three Distinct Methods in Pure Deciduous Stands
09:04

Leaf Area Index Estimation Using Three Distinct Methods in Pure Deciduous Stands

Published on: August 29, 2019

14.2K
Sampling for Estimating Frankliniella Species Flower Thrips and Orius Species Predators in Field Experiments
07:13

Sampling for Estimating Frankliniella Species Flower Thrips and Orius Species Predators in Field Experiments

Published on: July 17, 2019

9.8K

Area of Science:

  • Physiological Research
  • Biostatistics

Background:

  • Sample size estimation is vital for the validity and reproducibility of scientific research.
  • Current challenges in sample size estimation can compromise study outcomes.

Purpose of the Study:

  • To highlight the critical importance of accurate sample size estimation for physiological researchers.
  • To address existing problems and introduce standard methodologies for sample size determination.

Main Methods:

  • Illustrating the significance and current issues associated with sample size estimation.
  • Introducing commonly-used statistical methods for sample size calculation.
  • Detailing estimation processes and outcomes with practical examples.

Main Results:

  • Basic concepts and prerequisites for sample size estimation were defined.
  • Estimation procedures and results were demonstrated through specific examples under varying conditions.

Conclusions:

  • Achieving appropriate sample sizes necessitates adherence to essential premises.
  • The selection of suitable statistical analysis methods is a key requirement for accurate sample size computation.