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Updated: Feb 8, 2026

Multi-analyte Biochip MAB Based on All-solid-state Ion-selective Electrodes ASSISE for Physiological Research
Published on: April 18, 2013
Sensitivity and Selectivity of Ion-Selective Electrodes Interpreted Using the Nernst-Planck-Poisson Model
Jerzy J Jasielec1, Zekra Mousavi2, Kim Granholm2
1AGH University of Science and Technology , Faculty of Materials Science and Ceramics, Physical Chemistry and Modeling Department , Al. Mickiewicza 30 , 30-059 Kraków , Poland.
Abstract:
The Nernst-Planck-Poisson model is used for modeling the sensitivity and selectivity of ion-selective electrodes (ISEs) with plastic membranes. Two pivotal parameters characterizing ISE response are in focus: sensitivity and selectivity. An interpretation of sensitivity, which considers the concurrent influence of anions and cations on the ISE slope, is presented. The interpretation of selectivity shows the validity and limits of approaches hitherto taken to measure the true (unbiased) selectivity coefficient. The validity of more idealized interpretations by the diffusion-layer model is conceived.
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