Related Experiment Video

Updated: Feb 8, 2026

Evaluating the Effects of Different Polishing Methods on Color Stability of Dental Restorations in Pediatric Dentistry
03:37

Evaluating the Effects of Different Polishing Methods on Color Stability of Dental Restorations in Pediatric Dentistry

Published on: June 6, 2025

471

Pediatric Baseline Patch Test Series: Pediatric Contact Dermatitis Workgroup

JiaDe Yu, Amber Reck Atwater1, Bruce Brod2

  • 1Department of Dermatology, Duke University Medical Center, Durham, NC.

Dermatitis : Contact, Atopic, Occupational, Drug
|June 23, 2018
PubMed

Insights

A standardized pediatric patch test series was developed for children over six years old. This aims to improve the diagnosis of allergic contact dermatitis in pediatric patients.

Area of Science:

  • Pediatric Dermatology
  • Allergology
  • Contact Dermatitis

Background:

  • Allergic contact dermatitis presents diagnostic challenges in pediatric populations.
  • Epicutaneous patch testing, the gold standard for diagnosing contact sensitization, is underutilized in children compared to adults.

Purpose of the Study:

  • To develop and validate a standardized pediatric patch test series.
  • To create a reliable diagnostic tool for children over six years of age.

Main Methods:

  • A survey was conducted among dermatologists and allergists specializing in pediatric patch testing.
  • Data were collected from participants at the 2017 American Contact Dermatitis Society meeting.
  • A pediatric contact dermatitis working group reached a consensus on the test panel.

Main Results:

  • A consensus was reached on a baseline pediatric patch test panel.
  • The study established a standardized approach for pediatric patch testing.

Conclusions:

  • A foundational pediatric patch test series was successfully established through expert consensus.
  • This standardized panel is expected to aid in the diagnosis of allergic contact dermatitis in children.
Abstract

More Related Videos

Guidelines for Elective Pediatric Fiberoptic Intubation11:19

Guidelines for Elective Pediatric Fiberoptic Intubation

Published on: January 17, 2011

18.6K
Contact Hypersensitivity as a Murine Model of Allergic Contact Dermatitis08:25

Contact Hypersensitivity as a Murine Model of Allergic Contact Dermatitis

Published on: September 26, 2022

3.5K

Related Concept Videos

Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
266
Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight,...
320
Pharmacokinetics in Pediatric Patients: Drug Metabolism01:24

Pharmacokinetics in Pediatric Patients: Drug Metabolism

In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses...
239
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
305
Contact Angle01:13

Contact Angle

When a solid is dipped inside a liquid, the liquid surface becomes curved near the contact. For some solid–liquid interfaces, the liquid is pulled up along the solid, while for others, the liquid surface is convex or depressed near the solid surface. This phenomenon can be explained using the concept of cohesive and adhesive forces.
The adhesive force is the molecular force between molecules of different materials, that is, between the molecules of the solid and the liquid. The cohesive...
22.1K
Contact-dependent Signaling01:19

Contact-dependent Signaling

Contact-dependent signaling, as the name suggests, requires that communicating cells be in direct contact with each other. This is achieved either through receptor-ligand interactions or by specialized cytoplasmic channels that allow the flow of small molecules between cells. In animal cells, channels called gap junctions facilitate contact-dependent signaling in certain tissues, whereas, plasmodesmata perform a similar function in plants.
Gap Junctions
In animal cells, gap junctions are formed...
47.6K