Revealing the Genetic Instructions for Nervous System Wiring
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Updated: Feb 8, 2026

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Homarus Americanus Stomatogastric Nervous System Dissection
Published on: May 28, 2009
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1Smurfit Institute of Genetics and Institute of Neuroscience, Trinity College Dublin, Dublin 2, Ireland.
Trends in Neurosciences
|June 24, 2018
Abstract:
Why did the axon cross the midline? A 1993 paper by Corey Goodman and colleagues described a genetic screen in fruit flies that pioneered the discovery of conserved families of axon guidance cues and receptors, highlighting fundamental processes underlying wiring specificity in the developing nervous system.
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