Related Experiment Video
Updated: Feb 8, 2026

Murine Drinking Models in the Development of Pharmacotherapies for Alcoholism: Drinking in the Dark and Two-bottle Choice
Published on: January 7, 2019
Pharmacotherapy for Alcohol Use Disorder.
Stephen R Holt1, Daniel G Tobin2
1Department of Internal Medicine, Yale University School of Medicine, 1450 Chapel Street, Room P312, New Haven, CT 06511, USA.
Effective management of alcohol use disorder (AUD) involves personalized pharmacotherapy alongside counseling. This review guides clinicians on selecting appropriate medications for AUD patients, considering individual needs and treatment goals.
Area of Science:
- Addiction Medicine
- Pharmacology
- Psychiatry
Background:
- Alcohol use disorder (AUD) is a prevalent and serious condition often undertreated.
- Evolving understanding of AUD has led to advancements in management strategies.
- Current treatment integrates pharmacotherapy with non-drug interventions like counseling.
Purpose of the Study:
- To review available pharmacotherapeutic options for managing alcohol use disorder.
- To provide practical guidance for prescribers on selecting appropriate medications.
- To personalize patient care based on specific treatment goals and patient factors.
Main Methods:
- Literature review of pharmacologic treatments for AUD.
- Analysis of FDA-approved and off-label medication options.
- Consideration of factors influencing medication choice, including comorbidities and drug interactions.
Main Results:
- A range of pharmacologic agents are available for AUD treatment.
- Personalized treatment selection is crucial for optimal patient outcomes.
- Guidance is provided on the appropriate use of various medications.
Conclusions:
- Pharmacotherapy is a key component in the comprehensive management of alcohol use disorder.
- Clinicians can tailor medication selection to individual patient profiles.
- Further research and clinical experience will continue to refine AUD treatment approaches.
More Related Videos
05:12Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder
Published on: June 23, 2023
04:58Modeling Fetal Alcohol Spectrum Disorders in Zebrafish to Characterize the Impact of an Adverse Embryonic Environment on Adult Social Behavior
Published on: February 9, 2024
Related Concept Videos
Psychosis: Goals of Pharmacotherapy
Diabetes: Management and Pharmacotherapy
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Intrinsically Disordered Proteins
Oxidation of Alcohols
The process of oxidation in a chemical reaction is observed in any of the three forms:
Ethers from Alcohols: Alcohol Dehydration and Williamson Ether Synthesis
Ethers can be prepared from organic compounds by various methods. Some of them are discussed below,
Preparation of Ethers by Alcohol Dehydration
In this method, in the presence of protic acids, alcohol dehydrates to produce alkenes and ethers under different conditions. For example, in the presence of sulphuric acid, dehydration of ethanol at 413 K yields ethoxyethane, whereas it yields ethene at 443 K.
Protection of Alcohols
Protection
It defines a protecting group as the masking agent to make the more reactive species inert to a given set of conditions. This concept is depicted via the illustration of liquid flow through different outlets in an assembly of pipes. The analogy helps to understand the role...