Related Experiment Video
Updated: Jul 27, 2026
02:22
Full-Endoscopic Surgery for Hypothalamic Hamartoma Resection
Published on: April 12, 2024
984
Intractable Hiccups
Stasia Rouse1, Matthew Wodziak2
1Department of Neurology, Loyola University, Maywood, IL, USA.
Current Neurology and Neuroscience Reports
|June 24, 2018
Summary
Intractable hiccups lack formal treatment guidelines, often managed with older medications. Recent literature highlights pharmacologic options like dopamine blockers, baclofen, and gabapentin for effective hiccup management.
Area of Science:
- Neurology
- Gastroenterology
- Pulmonology
- Primary Care
Background:
- Hiccups are a common issue across various medical disciplines.
- Current treatment for intractable hiccups lacks formal guidelines, relying on anecdotal evidence and older medications.
Purpose of the Study:
- To review the recent literature on the management of intractable hiccups.
- To highlight current therapeutic options and their efficacy.
Main Methods:
- Literature review with an emphasis on studies from the last five years.
- Analysis of reported successful treatments for intractable hiccups.
Main Results:
- The production of hiccups involves complex neurotransmitter and anatomical pathways.
- Pharmacologic options including dopamine-blocking medications, baclofen, and gabapentin have shown success.
- Anticonvulsants are also noted as potentially useful treatments.
Conclusions:
- Intractable hiccups are a prevalent condition requiring effective management strategies.
- Several pharmacologic agents offer viable treatment options for intractable hiccups.
More Related Videos
Related Concept Videos
01:19Depolarizing Blockers: Pharmocokinetics
Depolarizing blockers are administered through intravenous injection. Succinylcholine is the most common choice of depolarizing blockers in emergency clinical practices. Although they have a rapid onset, they readily diffuse away from the motor end plate into the extracellular fluid. They are metabolized by enzymes such as liver butyrylcholinesterase and plasma pseudocholinesterases. This produces a short duration of action, typically 5-10 minutes long, unlike nondepolarizing blockers, which...
01:22Trachea
The trachea, commonly known as the windpipe, is a vital part of the human respiratory system. It serves as a passageway for air to travel between the larynx and the bronchi, allowing oxygen to reach the lungs. Let's explore its anatomical features, dimensions, layers of the tracheal wall, associated muscles, and the functions of its parts.
Anatomical Features:
Location: About half of the trachea is situated in the neck, anterior to the esophagus, and extends from the larynx (at the level of the...
Anatomical Features:
Location: About half of the trachea is situated in the neck, anterior to the esophagus, and extends from the larynx (at the level of the...
01:25Hyperpnea and Hyperventilation
Hyperventilation refers to a higher-than-normal rate and depth of breathing, often associated with anxiety attacks. This excessive breathing surpasses the body's need to expel CO2, leading to a condition known as hypocapnia - an unusually low level of carbon dioxide in the blood. Hypocapnia can constrict cerebral blood vessels, reducing blood flow to the brain, which may result in dizziness or fainting. Early signs include tingling and muscle spasms in the hands and face, caused by falling...
01:30Acute Respiratory Failure-III
Hypercapnic respiratory failure, also known as Type 2 or ventilatory respiratory failure, is a severe condition characterized by the body's inability to effectively remove carbon dioxide (CO2) from the bloodstream. It leads to an arterial CO2 pressure (PaCO2) exceeding 45 mmHg and a blood pH above 7.35. This situation indicates that the body's ventilatory demand, or the ventilation needed to maintain normal PaCO2 levels, surpasses its supply or the maximum gas flow achievable without causing...
01:11Pyloric Obstruction
Pyloric obstruction, also referred to as gastric outlet obstruction, is a condition characterized by narrowing or blockage at the pylorus—the muscular valve regulating the flow of stomach contents into the duodenum. When this passage becomes impaired, the stomach cannot effectively empty its contents into the small intestine. This disruption leads to a range of gastrointestinal symptoms, including early satiety, bloating, epigastric pain, postprandial nausea, persistent vomiting, and...
01:29Intestinal Obstruction I: Introduction
Intestinal obstruction is a partial or complete blockage of the small or large intestine that disrupts the normal flow of intestinal contents through the lumen. This interruption impairs digestion, absorption, and fluid balance, and may lead to serious complications if not treated promptly.Mechanical ObstructionMechanical obstruction occurs when a physical blockage prevents intestinal contents from passing, arising from within the lumen or the bowel wall, or from external compression.Adhesions,...