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Management of Subdural Hematomas: Part I. Medical Management of Subdural Hematomas
Elena I Fomchenko1, Emily J Gilmore2,3, Charles C Matouk4
1Department of Neurosurgery, Yale University, 20 York St, New Haven, CT, USA. elena.fomchenko@yale.edu.
Insights
Subdural hematomas (SDH) are a growing neurosurgical concern. This review details current medical management strategies for SDH, focusing on intracranial pressure, cerebral perfusion, and seizure control.
Area of Science:
- Neurosurgery
- Neurology
- Critical Care Medicine
Background:
- Subdural hematomas (SDH) pose significant neurosurgical challenges, marked by high morbidity, mortality, and recurrence rates.
- Increasing incidence is linked to an aging population and wider use of antiplatelet/anticoagulation therapies.
- Optimal medical and surgical management of SDH remains an active area of research.
Purpose of the Study:
- To review current medical management strategies for subdural hematomas (SDH).
- To provide an overview of recent literature and clinical trials concerning SDH care.
- To highlight key aspects of managing patients with SDH.
Main Methods:
- Review of Emergency Neurological Life Support (ENLS) guidelines for initial patient stabilization.
- Analysis of medical management principles including intracranial pressure (ICP) and cerebral perfusion pressure (CPP) maintenance.
- Examination of post-operative care and neurocritical care interventions for SDH patients.
Main Results:
- Initial management emphasizes maintaining critical physiological parameters (ICP, CPP, MAP, PaO2) and rapid diagnostic imaging.
- Medical care focuses on managing intracranial hypertension, ensuring adequate cerebral perfusion, seizure prevention, and supportive measures.
- Post-operative care involves intensive care unit (ICU) management by neurointensivists, addressing complications like increased ICP and seizures.
Conclusions:
- Effective SDH management requires a multidisciplinary approach, integrating emergency stabilization with comprehensive medical and critical care.
- Continued research into optimal treatment protocols is essential given the rising prevalence of SDH.
- Adherence to established guidelines and prompt intervention are crucial for improving outcomes in SDH patients.
Purpose Of Review:
Subdural hematomas (SDH) represent common neurosurgical problem associated with significant morbidity, mortality, and high recurrence rates. SDH incidence increases with age; numbers of patients affected by SDH continue to rise with our aging population and increasing number of people taking antiplatelet agents or anticoagulation. Medical and surgical SDH management remains a subject of investigation.
Recent Findings:
Initial management of patients with concern for altered mental status with or without trauma starts with Emergency Neurological Life Support (ENLS) guidelines, with a focus on maintaining ICP < 22 mmHg, CPP > 60 mmHg, MAP 80-110 mmHg, and PaO2 > 60 mmHg, followed by rapid sequence intubation if necessary, and expedited acquisition of imaging to identify a space-occupying lesion. Patients are administered anti-seizure medications, and their antiplatelet medications or anticoagulation may be reversed if neurosurgical interventions are anticipated, or until hemorrhage is stabilized on imaging. Medical SDH care focuses on (a) management of intracranial hypertension; (b) maintenance of adequate cerebral perfusion; (c) seizure prevention and treatment; (d) maintenance of normothermia, eucarbia, euglycemia, and euvolemia; and (e) early initiation of enteral feeding, mobilization, and physical therapy. Post-operatively, SDH patients require ICU level care and are co-managed by neurointensivists with expertise in treating increased intracranial pressure, seizures, and status epilepticus, as well as medical complications of critical illness. Here, we review various aspects of medical management with a brief overview of pertinent literature and clinical trials for patients diagnosed with SDH.
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