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Updated: Feb 8, 2026
09:41
Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
Published on: July 19, 2019
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Morphofunctional changes in distribution of pressure center in multiple sclerosis
Marius Cristian Neamţu1, Oana Maria Neamţu, Denisa Enescu Bieru
1Department of Sports Medicine and Kinesiology, University of Craiova, Romania; oanacristi_neamtu@yahoo.com.
Summary
Biomechanical analysis reveals distinct pressure distribution patterns in multiple sclerosis (MS) patients, impacting balance and gait initiation. These findings aid in understanding and managing motor performance deficits in MS.
Area of Science:
- Biomedical Engineering
- Clinical Biomechanics
- Neuroscience
Background:
- Gait and motor performance are critical in multiple sclerosis (MS) management.
- Complex biomechanical analysis, including center of pressure (DCP) and loading, offers new insights into MS patient balance.
- Pressure and force platforms are key tools for this analysis.
Purpose of the Study:
- To analyze the distribution of the center of pressure (DCP) and loading in MS patients.
- To differentiate balance and gait patterns between MS patients with and without clinically detectable gait disturbances.
- To understand how balance disorders affect gait initiation in MS.
Main Methods:
- 18 MS patients were studied, divided into two groups based on gait disturbance presence.
- Biomechanical analysis using force distribution platforms assessed loading and DCP.
- DCP analysis evaluated mediolateral stability, indicating pronation or supination.
Main Results:
- MS patients with gait disorders (Group 1) showed asymmetric left-right and anterior-posterior DCP distribution.
- Group 1 exhibited predominant pressure on the medial heel, metatarsals 1-3, and hallux.
- MS patients without gait disorders (Group 2) tended to distribute pressure on metatarsals 2-3 and less on the heel.
Conclusions:
- DCP and loading analysis are vital for assessing static equilibrium disorders and their impact on gait initiation.
- Anterior-posterior and mediolateral disorders in MS patients cause spatial-temporal distortions hindering gait.
- Predominant lateral heel pressure suggests a compensatory mechanism for balance and orientation correction during gait.
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