Supramolecular Analytical Chemistry in Cancer Research

Supramolecular interactions, such as those observed between antibodies and antigens, have been employed in developing analytical methods for several decades. One major area of interest concerns cancer research, where intricate supramolecular designs have emerged to tackle difficult analytes in complex tumor systems. Our increasing knowledge toward supramolecular systems have elicited profound interest in creating more efficient analytical approaches, evidenced by the ever-growing body of literature in the field. Some of the novel tools have indeed facilitated our understanding of cancer biology, through providing previously inaccessible information. In this review, we describe common strategies of developing supramolecular analytical methods and their implementations in cancer research. We provide an overview for each of the approaches and discuss representative examples in recent literature.