Related Experiment Video
Updated: Feb 8, 2026
07:46
A Minimally Invasive Method for Generating a Syngeneic Orthotopic Mouse Model of Lung Cancer
Published on: August 19, 2025
1.4K
[Immunotherapy in lung cancer: New concepts]
A-G Goubet1, A Livartowski2, E Romano3
1Centre d'immunothérapie des cancers, Inserm U932, 26, rue d'Ulm, 75005 Paris, France.
Revue Des Maladies Respiratoires
|June 27, 2018
Summary
Immune checkpoint inhibitors revolutionize lung cancer treatment by reactivating dormant immune cells. Further research into new immune targets promises novel therapeutic strategies against tumors.
Area of Science:
- Oncology
- Immunology
Background:
- The tumor microenvironment's complexity is increasingly understood.
- Immune checkpoints normally suppress immune responses against tumors.
Purpose of the Study:
- To review the role of immune checkpoint inhibitors in lung cancer.
- To discuss emerging immune targets for cancer therapy.
Main Methods:
- Review of current literature on immune checkpoint inhibitors.
- Analysis of novel immune targets in tumor immunology.
Main Results:
- Immune checkpoint inhibitors (ICIs) are effective in lung cancer by blocking inhibitory immune checkpoints.
- ICIs restore anti-tumor immune cell activity.
Conclusions:
- ICIs represent a significant advancement in lung cancer treatment.
- Understanding new immune targets will drive the development of next-generation cancer therapies.
Related Concept Videos
01:27Tumor Immunotherapy
2.0K
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
2.0K
01:19Self-Concept
1.7K
Self-concept is the cognitive and emotional understanding individuals hold about their identity. It evolves through various developmental stages, beginning in infancy and maturing as children grow. This concept influences how individuals perceive their abilities, interact with others, and manage challenges throughout life.
Infancy and Emerging Recognition
During infancy, self-concept is virtually nonexistent. Babies do not distinguish themselves as separate entities and often mistake their...
Infancy and Emerging Recognition
During infancy, self-concept is virtually nonexistent. Babies do not distinguish themselves as separate entities and often mistake their...
1.7K
01:24Concepts and Prototypes
552
The human nervous system handles vast amounts of information by translating sensory stimuli into neural impulses, which the brain processes, creating thoughts expressed through language or stored as memories. The brain also synthesizes information from emotions and memories, which significantly influence thoughts and behaviors. This intricate process creates a comprehensive mental picture.
The brain organizes this information using concepts, which are mental categories grouping linguistic data,...
The brain organizes this information using concepts, which are mental categories grouping linguistic data,...
552
02:56Formula Mass and Mole Concepts of Compounds
81.8K
Formula Mass of Covalent Compounds
81.8K
01:28Basic Concept
6.2K
Engineering mechanics is a branch of engineering that studies motion and the forces acting on objects. It is a fundamental subject and forms the basis of many other engineering disciplines. Length, time, mass, and force are some basic concepts in engineering mechanics.
Length, which measures the distance traveled by an object, is a fundamental concept in engineering mechanics. We use coordinates relative to a reference point to describe the distance. Length not only helps to describe the...
Length, which measures the distance traveled by an object, is a fundamental concept in engineering mechanics. We use coordinates relative to a reference point to describe the distance. Length not only helps to describe the...
6.2K
01:15Concept of Pressure at a Point
782
The concept of pressure at a point in a fluid establishes that pressure within a fluid is uniform in all directions at a specific location. This uniformity occurs because fluid molecules exert force evenly across any point due to their random motion and continuous collisions within the fluid. Pressure at a point is determined by the surrounding fluid molecules and is influenced by factors like depth and density, rather than by shape or orientation.
In a fluid at rest, pressure acts equally in...
In a fluid at rest, pressure acts equally in...
782