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Related Experiment Video

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Global Health Innovation Technology Models.

Kimberly Harding1

  • 1Monarch Innovation Partners, Inc, Rockville, USA.

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|June 27, 2018
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Summary

An Open Source-Open Science Architecture Framework can bridge technology gaps for global health innovation. Project Orchid aims to accelerate clinical trials and drug discovery in low-income countries.

Keywords:
AfricaBioinformaticsBusiness ProcessCROClinicalClinical ImagingClinical TrialsCommercializationDrug DiscoveryEpidemiologyFDAFrameworksGCPGlobal HealthHIVHardwareHealth Information ManagementHealth Information TechnologyICHImagingInfectious DiseasesInformaticsInnovationInteroperabilityLow Income CountriesLow Middle Income CountriesMalariaMedical DeviceNanomedicineNanotechnologyOpen ScienceOpen Source: Big DataProduct DevelopmentPublic HealthRadiologyRare DiseasesRegulatorySemanticsSoftwareStandardsSyntaxTBTanzaniaTropical DiseasesWHOehealthmHealth

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Area of Science:

  • Global Health
  • Health Informatics
  • Open Science

Background:

  • Persistent technology and business process disparities hinder global health innovation, particularly for infectious and rare diseases, between high-income, low-middle-income, and low-income countries.
  • Existing infrastructure limitations in low-income and low-middle-income countries impede collaborative research and sustainable innovation.

Purpose of the Study:

  • To propose an Open Source-Open Science Architecture Framework designed to address and bridge the technological and procedural divide in global health research collaboration.
  • To introduce Project Orchid, a conceptual Clinical Intelligence Exchange and Virtual Innovation platform, as a validation model for the proposed framework.

Main Methods:

  • Utilizing a hybrid approach integrating agnostic Open Source technology, healthcare interoperability standards, and Total Quality Management principles.
  • Developing Project Orchid as a platform to support multi-national clinical innovation efforts with local sustainability for low-income and low-middle-income country research cohorts.
  • Planning a validation phase involving 12 clinical research and public health organizations across six countries.

Main Results:

  • The proposed framework and platform aim to enable low-income and low-middle-income research organizations to enhance their clinical trial process maturity.
  • Anticipated outcomes include accelerated drug discovery, improved population health innovation, and strengthened public domain knowledge networks.
  • The platform is expected to reduce lag time in drug discovery and public health innovation.

Conclusions:

  • The Open Source-Open Science Architecture Framework offers a viable solution to overcome disparities in global health research.
  • Project Orchid has the potential to significantly improve clinical trial interventions and bio-surveillance through reliable clinical intelligence.
  • Successful implementation can foster more equitable and efficient global health innovation, benefiting both high-income and low-resource settings.