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Updated: Feb 8, 2026

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography
Published on: July 24, 2020
Optical coherence tomography for ocular surface and corneal diseases: a review
Nandini Venkateswaran1, Anat Galor1,2, Jianhua Wang1
11Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, McKnight Building Room 202A, 1638 NW 10th Avenue, 900 NW 17th Street, Miami, FL 33136 USA.
Abstract:
The advent of optical coherence tomography (OCT) imaging has changed the way ophthalmologists image the ocular surface and anterior segment of the eye. Its ability to obtain dynamic, high and ultra-high resolution, cross-sectional images of the ocular surface and anterior segment in a noninvasive and rapid manner allows for ease of use. In this review, we focus on the use of anterior segment OCT, which provides an "optical biopsy" or in vivo imaging of various ocular surface and corneal pathologies, allowing the clinician to diagnose diseases otherwise not visualized by traditional methods. The utility of anterior segment OCT for various anterior segment pathologies is reviewed.
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