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Protobothrops mucrosquamatus Bites to the Head: Clinical Spectrum from Case Series
Ying-Tse Yeh1, Min-Hui Chen2, Julia Chia-Yu Chang3,1
1Emergency Department, Taipei Veterans General Hospital, Taipei, Taiwan.
Abstract:
Protobothrops mucrosquamatus (Trimeresurus mucrosquamatus) is a medically important species of pit viper with a wide geographic distribution in Southeast Asia. Bites by P. mucrosquamatus mostly involve the extremities. Little is known about the toxic effects of P. mucrosquamatus envenoming to the head because of the infrequency of such occurrence. To better delineate the clinical manifestations of envenoming to the head, we report three patients who suffered from P. mucrosquamatus bites to the head and were treated successfully. All three patients developed progressive soft tissue swelling extending from head to neck, with two patients expanding further onto the anterior chest wall. Mild thrombocytopenia was noted in two patients. One patient had transient acute renal impairment and airway obstruction, necessitating emergent intubation. All three patients received high doses of species-specific antivenom with recovery within 1 week. No adverse reactions to antivenom were observed.
Insights
Head bites from Protobothrops mucrosquamatus pit vipers cause significant swelling and potential complications. Prompt treatment with species-specific antivenom led to successful recovery in all reported cases.
Area of Science:
- Herpetology
- Toxicology
- Clinical Medicine
Background:
- Protobothrops mucrosquamatus (Trimeresurus mucrosquamatus) is a medically significant pit viper in Southeast Asia.
- Envenomation typically affects extremities, with head bites being rare and poorly understood.
Observation:
- This report details three cases of P. mucrosquamatus bites to the head.
- Patients experienced progressive head and neck swelling, with two developing anterior chest wall involvement.
Findings:
- Two patients showed mild thrombocytopenia.
- One patient required intubation due to airway obstruction and acute renal impairment.
- All patients received high-dose, species-specific antivenom and recovered within a week without adverse reactions.
Implications:
- This study highlights the potential severity of P. mucrosquamatus head envenomation.
- It underscores the importance of timely and aggressive antivenom administration for favorable outcomes.
- Further research into the specific toxins and management of head envenomation is warranted.
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