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Updated: Feb 8, 2026

Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint
Published on: July 22, 2021
[Effect of surgical scope on postoperative fibrosis of knee joints]
Hai-Xiao Wu, Karen A Egiazaryan, Andrei P Ratyev
1Department of Bone and Soft Tissue Tumors, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China; drzhangchao@tmu.edu.cn.
Abstract:
Knee arthrofibrosis is a common complication after surgery, which is one of the key factors affecting the surgical outcome. It often causes the decrease of joint activity, chronic arthralgia, degeneration of cartilage tissues and joint disuse change, which seriously affects the daily life of the patients. How to reduce the occurrence of knee arthrofibrosis is the key to improve the expected effect of surgery, which is also an important problem to solve in clinical medicine; with our team's previous and recent research, we found that the degree of knee arthrofibrosis is closely related to the rang of the surgical. The use of minimally invasive and arthroscopic treatment can reduce the damage to synovial, cartilage and fat pad tissue, at the same time, combining with early postoperative rehabilitation training is the future effective prevention of postoperative arthrofibrosis of knee.
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