Related Experiment Video
Updated: Feb 8, 2026

Portable Thermographic Screening for Detection of Acute Wallenberg's Syndrome
Published on: September 19, 2019
Further observations on a bilateral IRVAN syndrome case
Álvaro Rodríguez1,2, Willy Carpio-Rosso3,4, Francisco J Rodríguez3,4
1Fundación Oftalmológica Nacional, Carrera 13 #13-50, Bogotá D.C., Colombia. fjrodriguez@fon.org.co.
Laser photocoagulation effectively treated idiopathic retinitis, vasculitis, retinal aneurysms, and neuroretinitis (IRVAN) in a bilateral case. Long-term follow-up showed prevention of neovascular complications and maintained visual acuity.
Area of Science:
- Ophthalmology
- Retinal Vascular Diseases
- Medical Imaging
Background:
- Idiopathic retinitis, vasculitis, retinal aneurysms, and neuroretinitis (IRVAN) is a rare condition affecting the retina.
- Long-term follow-up data on IRVAN syndrome is limited.
Observation:
- A 21-year-old female with bilateral IRVAN syndrome (stage 2 right eye, stage 3 left eye) presented with a history of laser photocoagulation for macroaneurysms and ischemia.
- Wide-field angiography and multimodal imaging revealed peripheral capillary nonperfusion and retinal findings.
Findings:
- Treatment with argon laser photocoagulation successfully prevented retinal neovascularization in both eyes over a long-term follow-up period.
- Normal visual acuity was maintained in one eye, and neovascular complications were averted.
Implications:
- Argon laser photocoagulation can be an effective treatment for preventing neovascular complications in IRVAN syndrome.
- Wide-field angiography and multimodal imaging are crucial for comprehensive assessment and monitoring of IRVAN disease.
Related Concept Videos
Naturalistic Observations
Observational Studies
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One...
Observational Learning
Actor-Observer Effect
Nephrotic Syndrome I : Introduction
Data Collection by Observations
An astronomer viewing the motion and brightness of stars in the sky and recording the data is an example of observational data collection. A botanist recording...

