Possible SAMe-induced mania

Hesitha Abeysundera1, Ramandeep Gill2

  • 1Psychiatry, Queensland Health, Cairns, Queensland, Australia.

BMJ Case Reports
|June 29, 2018
PubMed
Summary

Concurrent use of S-adenosyl-L-methionine (SAMe) and selective serotonin reuptake inhibitors (SSRIs) may trigger mania with psychotic features. This case report highlights the potential for serious psychiatric events when combining these substances.

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