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Published on: June 3, 2018
Transcatheter aortic valve implantation in Germany
Won-Keun Kim1,2, Christian W Hamm3,4
1Department of Cardiology, Kerckhoff Heart Center, 61231, Bad Nauheim, Germany.
Transcatheter aortic valve implantation (TAVI) has evolved significantly, becoming a preferred treatment for severe aortic stenosis, especially in elderly patients. German contributions have been pivotal in advancing TAVI through pioneering achievements and clinical practice integration.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
- Medical Device Technology
Background:
- Transcatheter aortic valve implantation (TAVI) has evolved from a novel procedure to a mature, integral treatment for severe aortic stenosis.
- Significant reductions in peri-procedural complications and mortality have established TAVI as a preferred therapy, particularly for elderly patients with high or prohibitive surgical risk.
Purpose of the Study:
- To highlight the significant contributions of Germany to the advancement of transcatheter aortic valve implantation (TAVI) technology and clinical practice.
- To showcase German pioneering achievements in TAVI, including early adoption, clinical trials, and procedural innovations.
Main Methods:
- Review of German involvement in first-in-man TAVI experiences.
- Analysis of participation in pivotal CE mark trials and randomized studies for TAVI devices.
- Examination of contributions to large TAVI registries and procedurally relevant aspects.
Main Results:
- Germany has been a leading nation in TAVI procedures and pioneering advancements.
- German involvement has been crucial in multiple phases of TAVI development, from initial trials to widespread clinical adoption.
- Pioneering German contributions have demonstrably impacted global TAVI clinical practice.
Conclusions:
- Germany has played a forefront role in the global evolution and adoption of TAVI.
- The collective efforts, including German innovations, have transformed TAVI into a standard treatment for severe aortic stenosis.
- Continued German engagement is vital for the future development and refinement of TAVI procedures.
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