Related Experiment Video
Updated: Feb 8, 2026

P50 Sensory Gating in Infants
Published on: December 26, 2013
Voltage-gated Sodium Channels in Sensory Information Processing
You Zhou1, Ping Pan1, Zhi-Yong Tan2
1Laboratory of Neuropharmacology and Neurotoxicology, Shanghai University, Shanghai 200444, China.
Abstract:
Objective & Background: Voltage-gated sodium channels (VGSCs) and potassium channels are critical in the generation of action potentials in the nervous system. VGSCs and potassium channels play important roles in the five fundamental senses of vision, audition, olfaction, taste and touch. Dysfunctional VGSCs are associated with clinical sensory symptoms, such as hyperpselaphesia, parosphresia, and so on. Conclusion: This short review highlights the recent advances in the study of VGSCs in sensory information processing and discusses the potential role of VGSCs to serve as pharmacological targets for the treatment of sensory system diseases.
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