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Updated: Feb 8, 2026

Transthoracic Echocardiography in Mice
Published on: May 28, 2010
Clinical study of stand-alone transthoracic echocardiography-guided percutaneous occlusion of patent ductus
Hua Cao1, Qiang Chen, Gui Can Zhang
1Department of Cardiovascular Surgery, Union Hospital, Fujian Medical University; Fuzhou-P. R. China. caohua0791@163.com.
Objective:
We aimed to investigate the feasibility and safety of stand-alone transthoracic echocardiography-guided percutaneous occlusion of patent ductus arteriosus (PDA) without the use of X-ray equipment.
Methods:
From January to December 2015, we performed stand-alone transthoracic echocardiography-guided percutaneous PDA occlusion using an occluder delivered via a delivery sheath introduced via femoral vein access without the use of X-ray equipment in 12 PDA patients.
Results:
PDA occlusion was successfully performed in all 12 patients. The procedure duration ranged from 30 to 110 min (50.4±22.8 min), and the size of the implanted occluder ranged from 12 to 20 mm (15.2±2.8 mm). No occluder migration, residual shunt, or thrombotic complications were observed in the perioperative period. There was no clinical death, hemolysis, infection, or embolism during patients' hospitalization and the follow-up period.
Conclusion:
Stand-alone transthoracic echocardiography-guided percutaneous PDA occlusion without the use of X-ray equipment is a safe and effective procedure.
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