[Total duodenopancreatectomy for non-secreting pancreatic nesidioblastoma]

Non-secreting tumors of pancreatic islets of Langerhans are now rarely encountered as a result of the increasing performance of techniques for detecting the different hormones of insular origin or their precursors. Histologically, these tumors, that can be termed nesidioblastomas of the pancreas, have a poorly defined potential course, but there is a definite risk of malignancy. A case is reported of a pancreatic nesidioblastoma located in two regions, treatment being by total duodenopancreatectomy with a good result at 4-year follow up review. A bibliographic list of 13 published reports in the international literature is provided.