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Lacrimal Canaliculus Imaging Using Optical Coherence Tomography Dacryography.

Masahiro Fujimoto1, Akihito Uji2, Ken Ogino1

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Optical coherence tomography dacryography (OCTD) offers high-resolution, non-invasive imaging of the lacrimal canaliculus (LC). This novel technique allows for simultaneous evaluation of LC morphology and function, aiding in diagnosing tear drainage disorders.

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Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Biomedical Engineering

Background:

  • The lacrimal canaliculus (LC) is crucial for tear drainage.
  • Existing methods for evaluating the LC lack detail and are often invasive.
  • A need exists for advanced imaging techniques to assess LC structure and function.

Purpose of the Study:

  • To introduce and evaluate a novel optical coherence tomography dacryography (OCTD) technique for high-resolution, non-invasive imaging of the lacrimal canaliculus.
  • To assess the capability of OCTD in visualizing LC morphology and evaluating its function.
  • To determine the clinical utility of OCTD in patients with lacrimal drainage system disorders.

Main Methods:

  • Three-dimensional OCT images of the LC were acquired non-invasively through the palpebral conjunctiva.
  • The study included 20 healthy volunteers and 10 patients with lacrimal disorders.
  • LC function was assessed by measuring intraluminal signal intensity changes over time after contrast agent instillation.

Main Results:

  • OCTD provided high-resolution, three-dimensional images of the LC, revealing morphological differences between segments.
  • The technique successfully visualized LC structures in patients with punctal and canalicular obstructions, aiding in surgical planning.
  • No significant differences in LC morphology or function were found between patients with nasolacrimal duct obstruction (NLDO) and healthy subjects.

Conclusions:

  • OCTD is a promising non-invasive tool for detailed lacrimal canaliculus imaging.
  • This technique enables simultaneous quantitative evaluation of both LC morphology and function.
  • OCTD facilitates improved diagnosis and management of lacrimal drainage system disorders.