Human-enteric-coronaviruslike particles (CVLP) with different epidemiological characteristics

Area of Science:

• Virology
• Epidemiology
• Public Health

Background:

• Coronaviruses are a significant cause of illness in children.
• Understanding the prevalence and seasonality of coronaviruses is crucial for public health interventions.

Purpose of the Study:

• To investigate the prevalence and seasonality of coronavirus particles (CVLP) in diarrheic and control children in Gabon.
• To explore potential correlations between CVLP prevalence and climatological factors.

Main Methods:

• Electron microscopy was used to examine stool samples from 156 diarrheic and 115 control children.
• Stool samples were collected over a year in Haut-Ogooué, Gabon.
• Prevalence data were analyzed in relation to age and season.

Main Results:

• Coronavirus particles (CVLP) were detected in 38.5% of diarrheic children and 65.2% of controls.
• CVLP prevalence showed seasonal variation in both groups.
• In controls, CVLP were more prevalent in children over 2 years old and during rainy seasons; however, diarrheic children showed lower CVLP prevalence during rainy seasons.

Conclusions:

• Coronavirus particles (CVLP) are present in children in Gabon, with seasonal variations.
• The relationship between CVLP, age, and season differs between diarrheic and control children.
• Further research is needed to identify specific climatological factors influencing CVLP prevalence.