Related Experiment Video
Updated: Feb 8, 2026

Acute and Chronic Tactile Sensory Testing after Spinal Cord Injury in Rats
Published on: April 4, 2012
Myeloid cell responses after spinal cord injury
Samuel David1, Antje Kroner2, Andrew D Greenhalgh3
1Centre for Research in Neuroscience, The Research Institute of the McGill University Health Center, 1650 Cedar Ave., Montreal, Quebec H3G 1A4, Canada.
Abstract:
The past decade has revealed much about the complexity of the local inflammatory response after spinal cord injury (SCI). A major challenge is to distinguish between microglia and monocyte-derived macrophages (MDMs) to determine their phenotype and function. Transcriptome studies have revealed microglia-selective genes but are still limited in scope because many markers are downregulated after injury. Additionally, new genetic reporter mice are available to study microglia and MDMs. There is more evidence now for the plasticity and heterogeneity of microglia and MDMs. We also discuss the role of neutrophils that are the first peripheral cells to enter the injured CNS.
Related Concept Videos
Spinal Cord
The Spinal Cord
Spinal Cord: Information Processing
Sensory Information Processing
Sensory information processing begins at the sensory receptors located in the skin and other tissues, which detect somatic sensory stimuli such as touch, temperature, or pain. These receptors function as catalysts, initiating...
Spinal Cord: Gross Anatomy
Spinal Cord: Cross-sectional Anatomy
Gray Matter and its Components
Central to the gray matter is...
Differentiation of Common Myeloid Progenitor Cells

