Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Electrophysiologic study in benign human botulism type B.

A Cruz Martínez, B Anciones, M T Ferrer

    Muscle & Nerve
    |September 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Age, sex, and gender distribution of neurology faculty in Spain: Results of a national survey by the Spanish Society of Neurology.

    Neurologia·2026
    Same author

    [Cardiovascular safety of new drugs for the acute and preventive treatment of migraine: gepants and ditans].

    Revista de neurologia·2023
    Same author

    Acute stroke care during the COVID-19 pandemic. Ictus Madrid Program recommendations.

    Neurologia·2020
    Same author

    Reply to letter "Remarks on cerebral infarct from another point of view".

    Neurologia (Barcelona, Spain)·2014
    Same author

    Prevalence and severity of hepatopulmonary syndrome and its influence on survival in cirrhotic patients evaluated for liver transplantation.

    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2014
    Same author

    Clinical management guidelines for subarachnoid haemorrhage. Diagnosis and treatment.

    Neurologia (Barcelona, Spain)·2012
    Same journal

    Late-Onset Myasthenia Gravis: An Increasingly Frequent Clinical Entity With Distinctive Challenges.

    Muscle & nerve·2026
    Same journal

    Clinical Characteristics and Treatment Management of Seronegative Myasthenia Gravis: A Systematic Review of the Literature.

    Muscle & nerve·2026
    Same journal

    Muscle-Specific Kinase Signaling and Its Therapeutic Potential.

    Muscle & nerve·2026
    Same journal

    Optimization of the Cell-Based Assay Methodology to Study Degradation of Acetylcholine Receptors (Antigenic Modulation) by Antibodies From Myasthenia Gravis Patients.

    Muscle & nerve·2026
    Same journal

    Review of Congenital Myasthenic Syndrome Caused by Pathogenic Variants in GFPT1.

    Muscle & nerve·2026
    Same journal

    Accuracy of Palpation-Guided Versus First Attempt at Ultrasound-Guided Electromyography Needle Placement for the Extensor Carpi Radialis Longus and Brevis by Trainees.

    Muscle & nerve·2026
    See all related articles

    Single fiber EMG (SFEMG) revealed increased jitter and impulse blocking in a patient with botulism, indicating neuromuscular junction dysfunction. These abnormalities improved with clinical recovery, suggesting ultraterminal sprouting.

    Area of Science:

    • Neurology
    • Electrophysiology

    Background:

    • Botulism can cause autonomic dysfunction and cranial nerve paresis.
    • Conventional electromyography (EMG) may not detect subtle neuromuscular junction abnormalities.

    Observation:

    • A 64-year-old diabetic woman with mild botulism presented with autonomic dysfunction and cranial nerve paresis.
    • Conventional EMG showed mild peripheral neuropathy related to diabetes; repetitive nerve stimulation was normal.

    Findings:

    • Single-fiber EMG (SFEMG) demonstrated increased jitter and impulse blocking in clinically unaffected muscles.
    • Jitter was frequency-dependent and improved with higher innervation rates.
    • Progressive increase in motor unit fiber density suggested new endplate formation or sprouting.

    Related Experiment Videos

    Implications:

    • SFEMG is a sensitive tool for detecting subclinical neuromuscular junction abnormalities in botulism.
    • Findings suggest ultraterminal sprouting and new endplate formation may contribute to recovery.
    • Early detection and monitoring of neuromuscular junction function are crucial in botulism management.