Related Experiment Video
Updated: Feb 8, 2026
07:31
A Computerized Functional Skills Assessment and Training Program Targeting Technology Based Everyday Functional Skills
Published on: February 13, 2020
7.5K
Which mental disorders are associated with the greatest impairment in functioning?
Mark J Edlund1, Jiantong Wang2, Kristen Gulledge Brown3
1Behavioral and Urban Health, RTI International, 3040 E. Cornwallis Road, P.O. Box 12194, Research Triangle Park, NC, 27709-2194, USA. medlund@rti.org.
Social Psychiatry and Psychiatric Epidemiology
|July 1, 2018
Summary
Mental health disorders significantly impact daily functioning. Mood disorders showed the greatest functional impairment, followed by anxiety and substance use disorders, underscoring the need for comprehensive assessment tools.
Area of Science:
- Psychiatry
- Mental Health Research
- Public Health
Background:
- Functional impairment is a key outcome in mental health.
- Existing measures of disability may not fully capture the impact of various mental disorders.
- Understanding these associations is crucial for effective treatment and support.
Purpose of the Study:
- To compare the associations between specific mental disorders and three distinct measures of functional impairment.
- To evaluate the Global Assessment of Functioning (GAF), days out of role, and the World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0).
Main Methods:
- Secondary analysis of a large, nationally representative US dataset (n=5653).
- Utilized generalized linear models to assess independent effects of mental disorders.
- Controlled for comorbidity, physical health, and sociodemographic factors.
Main Results:
- Associations between mental disorders and functional impairment varied by assessment tool.
- Mood disorders were generally linked to the most significant functional impairment.
- Anxiety disorders showed intermediate impairment, while substance use disorders were associated with the least.
Conclusions:
- The findings emphasize the importance of using multiple, complementary measures to assess functional impairment.
- Different mental disorders have varying impacts on daily life, necessitating tailored evaluation approaches.
Related Concept Videos
01:10Higher Mental Functions of the Brain: Language
3.9K
Language is a system of communication that allows the expression of thoughts, ideas, and feelings. The brain processes language in both hemispheres.
Language formation and comprehension take place in the dominant hemisphere. The dominant hemisphere is responsible for understanding the meaning of spoken, written, or sign language, as well as the ability to communicate. For most people, the left hemisphere is the dominant one. The right hemisphere, then, gives tone and emotional context to the...
Language formation and comprehension take place in the dominant hemisphere. The dominant hemisphere is responsible for understanding the meaning of spoken, written, or sign language, as well as the ability to communicate. For most people, the left hemisphere is the dominant one. The right hemisphere, then, gives tone and emotional context to the...
3.9K
01:27Diagnostic and Statistical Manual of Mental Disorders (DSM)
1.2K
The Diagnostic and Statistical Manual of Mental Disorders (DSM) serves as the primary classification system for mental health disorders, providing standardized diagnostic criteria for clinicians and researchers. First published by the American Psychiatric Association (APA) in 1952, the DSM has undergone several revisions to reflect evolving psychiatric understanding. The fifth edition, DSM-5, released in 2013, introduced key updates that expanded diagnostic categories and modified diagnostic...
1.2K
01:26Higher Mental Functions of Brain: Learning and Memory
2.1K
Memory is one of the most vital higher mental functions of the brain. Memory is closely related to learning because it enables us to retain information and experiences from our past to use them in our present life. It also helps us to remember facts, events, and skills, such as riding a bike or swimming. There are two types of memory — declarative memory, which involves memorizing facts or events, and procedural memory, which enables us to remember how to do something like writing or...
2.1K
01:30Stress and Mental Health
955
Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms.
Individuals with depression often experience challenges in both their personal and professional...
Individuals with depression often experience challenges in both their personal and professional...
955
02:18Intrinsically Disordered Proteins
19.6K
Intrinsically disordered proteins are a group of proteins that do not fold into specific three-dimensional structures. Their structural flexibility allows them to complement ordered proteins to perform functions that are inaccessible to rigid structures. They are more common in eukaryotes than prokaryotes and may either be exclusively intrinsically disordered or hybrid proteins, consisting of a mix of ordered and disordered regions. The absence of a rigid structure in these proteins can be...
19.6K
01:17Factors Affecting Renal Clearance: Renal Impairment
480
Renal dysfunction significantly impairs the renal clearance of drugs, leading to potential complications in drug therapy. Renal failure, which can be caused by various factors, poses a significant challenge in the elimination of drugs from the body.
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
480