Related Experiment Video
Updated: Feb 8, 2026
04:44
Inter-Brain Synchrony in Open-Ended Collaborative Learning: An fNIRS-Hyperscanning Study
Published on: July 21, 2021
5.0K
Prevalence and Comorbidities of Resistant Hypertension: A Collaborative Population-Based Observational Study.
Simone Romano1, Chiara Idolazzi1, Cristiano Fava1
1Section of General Medicine and Hypertension, Department of Medicine, University of Verona, Policlinico GB Rossi, Piazzale LA Scuro 10, 37134, Verona, Italy.
Summary
Resistant hypertension affects 2.1% of adults, often linked to diabetes and heart disease. These patients face significant cardiovascular risks despite multiple treatments.
Area of Science:
- Cardiology
- Hypertension Research
- Public Health
Background:
- Resistant hypertension is a serious condition associated with elevated cardiovascular risk.
- Understanding its prevalence and associated factors is crucial for patient management.
Purpose of the Study:
- To determine the prevalence of resistant hypertension in the Verona urban area.
- To investigate the association between resistant hypertension and cardiovascular risk factors or diseases.
Main Methods:
- An observational study involving 17,502 adult subjects.
- Resistant hypertension defined as treatment with ≥4 antihypertensive medications.
- Clinical characteristics analyzed in a subsample of 55 patients.
Main Results:
- Hypertension prevalence was 21.9%; resistant hypertension was 2.1%.
- High rates of diabetes (53%), hyperlipidemia (83%), carotid stenosis (45%), ischemic heart disease (43%), and left ventricular hypertrophy (40%) were observed.
- Elevated blood pressure persisted in 58% of patients on multiple medications.
Conclusions:
- Resistant hypertension patients exhibit higher pressures and significant cardiovascular risk.
- High prevalence of risk factors, organ damage, and cardiovascular disease underscores the severity.
Related Concept Videos
01:11Observational Studies
11.1K
Observational studies are a type of analytical study where researchers observe events without any interventions. In other words, the researcher does not influence the response variable or the experiment's outcome.
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One...
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One...
11.1K
01:08Prevalence and Incidence
1.9K
In statistical epidemiology and health sciences, two essential metrics—prevalence and incidence—are fundamental for understanding disease dynamics within a population. These measures enable public health officials, epidemiologists, and researchers to assess the burden of diseases, allocate resources effectively, and design impactful public health policies and interventions.
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
1.9K
02:04Conservation of Small Populations
17.4K
Small population sizes put a species at extreme risk of extinction due to a lack of variation, and a consequent decrease in adaptability. This weakens the chances of survival under pressures such as climate change, competition from other species, or new diseases. Large populations are more likely to survive pressures such as these, as such populations are more likely to harbor individuals that have genetic variants that are adaptive under new stresses. Small populations are much less...
17.4K
01:30Hypertension III: Clinical Manifestations and Diagnostic Studies
585
Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
585
01:25What is Population Genetics?
64.8K
A population is composed of members of the same species that simultaneously live and interact in the same area. When individuals in a population breed, they pass down their genes to their offspring. Many of these genes are polymorphic, meaning that they occur in multiple variants. Such variations of a gene are referred to as alleles. The collective set of all the alleles within a population is known as the gene pool.
64.8K
01:29Chronic Pancreatitis II: Collaborative Care
376
The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
Assessment:
376