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Childhood pilomatricomas: Associated anomalies
Camile Richet1, Aude Maza1, Isabelle Dreyfus1
1Larrey Hospital, Paul Sabatier University, Toulouse, France.
Pediatric Dermatology
|July 3, 2018
Summary
Pilomatricoma, a common pediatric tumor, may indicate underlying genetic conditions, especially when multiple lesions appear. Early diagnosis and family history review are crucial for proper management.
Area of Science:
- Pediatric Oncology
- Dermatology
- Clinical Genetics
Background:
- Pilomatricoma is a frequent benign skin tumor observed in pediatric patients.
- Management guidelines for pilomatricoma are essential for clinicians.
- Associated systemic diseases can occur with pilomatricoma.
Purpose of the Study:
- To review the literature on pilomatricoma in children.
- To aid clinicians in managing pediatric pilomatricoma cases.
- To identify potential associated conditions and guide diagnostic approaches.
Main Methods:
- Comprehensive literature review of PubMed database.
- Utilized exhaustive Medical Subject Heading (MeSH) terms.
- Analyzed retrospective series and case reports involving 1,458 children.
Main Results:
- Identified 32 children (2.2%) with associated diseases.
- Multiple pilomatricomas were more frequently linked to associated conditions (23/32 cases).
- Single pilomatricoma lesions were associated with diseases in 9 cases.
Conclusions:
- Reassure families and conduct thorough medical/family history interviews.
- Perform clinical examinations for specific genetic syndromes (e.g., Turner, Kabuki).
- Recommend long-term clinical follow-up; paraclinical tests are indicated for anomalies or positive family history.
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